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Clinical Research Project Manager III Salary in the United States

How much does a Clinical Research Project Manager III make in the United States?

As of July 01, 2026, the average salary for a Clinical Research Project Manager III in the United States is $100,836 per year, which breaks down to an hourly rate of $48.

However, a Clinical Research Project Manager III's salary can vary significantly. Here’s a look at the typical salary range:

  • Top Earners (90th percentile): $123,194
  • Majority Range (25th-75th percentile): $89,338 to $112,539
  • Entry-Level (10th percentile): $78,870
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View as table View as graph 25% $89,338 10% $78,870 90% $123,194 75% $112,539 $100,836 50%(Median) Didn’t find job title? Click

Clinical Research Project Manager III Salaries by Percentile

Annual
Salary		 Monthly
Pay		 Weekly
Pay		 Hourly
Wage
75th Percentile $112,539 $9,378 $2,164 $54
Average $100,836 $8,403 $1,939 $48
25th Percentile $89,338 $7,445 $1,718 $43
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Key Factors That Influence Clinical Research Project Manager III Salaries

A Clinical Research Project Manager III's salary isn't a fixed number. It's shaped by several important factors. Below, we'll explore how your years of experience, geographic location, and company size can directly affect your earning potential.

How Experience Level Affects Clinical Research Project Manager Salaries?

Experience is a primary driver of a Clinical Research Project Manager III's salary. As you build your skills and take on more complex tasks, your compensation generally increases. Here's how the average salary grows at different career stages:

  • Clinical Research Project Manager I (0-2 years): $62,898
  • Clinical Research Project Manager II (2-4 years): $86,101
  • Clinical Research Project Manager III (4-7 years): $100,836
  • Clinical Research Project Manager IV (7+ years): $114,706
  • Clinical Research Project Manager V (7-10 years): $141,634
Job Role Years of Experience Average Salary
Clinical Research Project Manager I0-2 years$62,898
Clinical Research Project Manager II2-4 years$86,101
Clinical Research Project Manager III4-7 years$100,836
Clinical Research Project Manager IV7+ years$114,706
Clinical Research Project Manager V7-10 years$141,634
$62,898 Clinical ...
$86,101 Clinical ...
$100,836 Clinical ...
$114,706 Clinical ...
$141,634 Clinical ...
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What Am I Worth?

Top Paying Cities for Clinical Research Project Manager IIIs

Salaries can also vary between different cities. Major metropolitan areas or cities with a high demand for technicians often offer more competitive pay. Here are a few examples of average annual salaries in different U.S. cities:

  • San Jose: $127,184
  • San Francisco: $125,792
  • Oakland: $123,141

Clinical Research Project Manager III Salary by Company Size: Startups vs. Enterprise

Clinical Research Project Manager III salary potential scales significantly with company size. Data shows that Enterprise companies (5,000+ employees) pay the highest average salary at around $114,356. While startup companies pay approximate $97,014.

Clinical Research Project Manager III Salary by Company Size

Company Size Employees Average Salary
Startup1~50$97,014
Growth Stage51~500$102,524
Established501~5000$110,510
Enterprise5000+$114,356

Clinical Research Project Manager III Salary by Industry: Top Paying Sectors

For Clinical Research Project Manager III roles, the industry you choose can affect earning potential by as much as 40% (the gap between the highest and lowest paying industries). Data shows that the Biotechnology and Healthcare sectors offer the strongest compensation, at 20% above the average. In contrast, Clinical Research Project Manager positions in Chemicals or Edu., Gov't. & Nonprofit typically offer lower base pay, as these industries often view Clinical Research Project Manager III as a support function rather than a direct revenue driver.

The top paying industries for a Clinical Research Project Manager III

Industry Sector Average Annual Salary Average Hourly Rate Pay vs.Avg
Biotechnology$121,003$58.020%
Healthcare$110,920$53.010%

Clinical Research Project Manager III Salary: Hourly Rate, Weekly Pay, and Monthly Pay

Understanding how a Clinical Research Project Manager III's annual salary breaks down can help with budgeting. Below, you can see the average hourly rate, weekly pay, and monthly pay for this role. Use the buttons to switch between different pay periods.

  • Hourly
  • Monthly
  • Weekly
  • Yearly
  • Table View
Last Updated on July 01, 2026
$89,338
Average $100,836/year
$112,539
$7,445
Average $8,403/month
$9,378
$1,718
Average $1,939/week
$2,164
$43
Average $48/hour
$54
Annual Salary Monthly Pay Weekly Pay Hourly Wage
75th Percentile $112,539 $9,378 $2,164 $54
Average $100,836 $8,403 $1,939 $48
25th Percentile $89,338 $7,445 $1,718 $43

Clinical Research Project Manager III Salary Growth & Career Path

Clinical Research Project Manager III
Clinical Research Project Manager IV
VP of Clinical Research Project Management

For a Clinical Research Project Manager III, the most direct path to higher earnings is advancing to the Clinical Research Project Manager IV role. This promotion typically comes with a significant pay increase, bringing the average annual salary to $114,706 - a projected growth of 14% over your current level.

Salaries of jobs related to Clinical Research Project Manager III

Most common benefits for Clinical Research Project Manager III

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Common company salaries for Clinical Research Project Manager III

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FAQ about Clinical Research Project Manager III

1. Where can a Clinical Research Project Manager III earn the most?

A Clinical Research Project Manager III's earning potential can vary widely depending on several factors, including location, industry, experience, education, and the specific employer. According to the latest salary data by Salary.com, a Clinical Research Project Manager III earns the most in San Jose, CA, where the annual salary of a Clinical Research Project Manager III is $127,184.

2. What is the highest pay for Clinical Research Project Manager III?

The highest pay for Clinical Research Project Manager III is $123,194.

3. What is the lowest pay for Clinical Research Project Manager III?

The lowest pay for Clinical Research Project Manager III is $78,870.

4. What are the responsibilities of Clinical Research Project Manager III?

Manages and oversees all aspects of clinical research projects. Ensures projects are timely, are evaluating accurate data, and are producing precise results. Plans, directs, creates, and communicates the study timeline. Develops detailed project plans, and monitors project milestones against performance indicators. Ensures the project is planned and conducted in accordance with all applicable regulations, standard operating procedures, and good clinical practices (GCP). Manages risk assessment and mitigation. Generates reports to provide periodic status updates. Requires a bachelor's degree. Typically reports to a manager. Work is generally independent and collaborative in nature. Contributes to moderately complex aspects of a project. Typically requires 4-7 years of related experience.

5. What industry pays the highest salary for Clinical Research Project Manager III?

The Biotechnology industry offers the highest average compensation for Clinical Research Project Manager III roles, with salaries approximately 20% above the market median.

Where Does Our Salary Data Come From?

Salary.com provides salary estimates, histograms, trends, and comparisons using data from employer job postings and third-party sources.

We offer detailed salary information across multiple percentiles for your reference. (Click here to learn Why the Salary Midpoint Formula Is Crucial for Achieving Pay Equity.)

With the most extensive online, real-time compensation data available, Salary.com helps you pinpoint your exact pay target.

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