In California, the law permits registered nurses and physician assistants to administer Botox injections, provided they do so under the supervision of a licensed physician. This means that while nurses can perform these cosmetic procedures, they must operate within the framework of a collaborative practice agreement with a supervising physician. The regulations do not specify particular locations for these treatments, allowing them to be performed in various healthcare settings, including medical offices and aesthetic clinics. It is essential for nurses to have the appropriate training and certification in order to ensure patient safety and effective outcomes. Additionally, the supervising physician is responsible for overseeing the treatment process, which includes ensuring that the nurse is adequately trained and that all safety protocols are followed. This collaborative approach helps maintain high standards of care in the administration of Botox and other cosmetic injectables.