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Clinical Trial Project Management Manager, Sr. Salary in the United States

How much does a Clinical Trial Project Management Manager, Sr. make in the United States?

As of August 01, 2026, the average salary for a Clinical Trial Project Management Manager, Sr. in the United States is $146,930 per year, which breaks down to an hourly rate of $71.

However, a Clinical Trial Project Management Manager, Sr.'s salary can vary significantly. Here’s a look at the typical salary range:

  • Top Earners (90th percentile): $175,415
  • Majority Range (25th-75th percentile): $135,240 to $161,840
  • Entry-Level (10th percentile): $124,597
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View as table View as graph 25% $135,240 10% $124,597 90% $175,415 75% $161,840 $146,930 50%(Median) Didn’t find job title? Click

Clinical Trial Project Management Manager, Sr. Salaries by Percentile

Annual
Salary		 Monthly
Pay		 Weekly
Pay		 Hourly
Wage
75th Percentile $161,840 $13,487 $3,112 $78
Average $146,930 $12,244 $2,826 $71
25th Percentile $135,240 $11,270 $2,601 $65
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Key Factors That Influence Clinical Trial Project Management Manager, Sr. Salaries

A Clinical Trial Project Management Manager, Sr.'s salary isn't a fixed number. It's shaped by several important factors. Below, we'll explore how your years of experience, geographic location, and company size can directly affect your earning potential.

How Experience Level Affects Clinical Trial Project Management Manager, Sr. Salaries?

Experience is a primary driver of a Clinical Trial Project Management Manager, Sr.'s salary. As you build your skills and take on more complex tasks, your compensation generally increases. Here's how the average salary grows at different career stages:

  • Clinical Study Project Management Supervisor (10+ years): $97,243
  • Clinical Study Project Management Manager (10+ years): $121,643
  • Clinical Trial Project Management Manager, Sr. (10+ years): $146,923
  • Clinical Study Project Management Director (10+ years): $167,931
  • VP of Clinical Study Project Management (10+ years): $218,111
Job Role Years of Experience Average Salary
Clinical Study Project Management Supervisor10+ years$97,243
Clinical Study Project Management Manager10+ years$121,643
Clinical Trial Project Management Manager, Sr.10+ years$146,923
Clinical Study Project Management Director10+ years$167,931
VP of Clinical Study Project Management10+ years$218,111
$97,243 Clinical ...
$121,643 Clinical ...
$146,923 Clinical ...
$167,931 Clinical ...
$218,111 VP of Cli...
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What Am I Worth?

How Do Clinical Trial Project Management Manager, Sr. Salaries Vary from State to State?

Your salary can change significantly depending on where you work. States with a higher cost of living and strong industrial sectors often pay more to attract Clinical Trial Project Management Manager, Sr.s. For example, consider the average annual salaries in these key locations:

  • District of Columbia: $162,680.
  • California: $162,060.
  • Massachusetts: $159,900.

Top Paying Cities for Clinical Trial Project Management Manager, Sr.s

Salaries can also vary between different cities. Major metropolitan areas or cities with a high demand for technicians often offer more competitive pay. Here are a few examples of average annual salaries in different U.S. cities:

  • San Jose: $185,320
  • San Francisco: $183,290
  • Oakland: $179,430

Clinical Trial Project Management Manager, Sr. Salary by Company Size: Startups vs. Enterprise

Clinical Trial Project Management Manager, Sr. salary potential scales significantly with company size. Data shows that Enterprise companies (5,000+ employees) pay the highest average salary at around $166,735. While startup companies pay approximate $141,485.

Clinical Trial Project Management Manager, Sr. Salary by Company Size

Company Size Employees Average Salary
Startup1~50$141,485
Growth Stage51~500$149,514
Established501~5000$161,120
Enterprise5000+$166,735

Clinical Trial Project Management Manager, Sr. Salary by Industry: Top Paying Sectors

For Clinical Trial Project Management Manager, Sr. roles, the industry you choose can affect earning potential by as much as 60% (the gap between the highest and lowest paying industries). Data shows that the Healthcare and Chemicals sectors offer the strongest compensation, at 40% above the average. In contrast, Clinical Trial Project Management Manager, Sr. positions in Pharmaceuticals or Biotechnology typically offer lower base pay, as these industries often view Clinical Trial Project Management Manager, Sr. as a support function rather than a direct revenue driver.

The top paying industries for a Clinical Trial Project Management Manager, Sr.

Industry Sector Average Annual Salary Average Hourly Rate Pay vs.Avg
Healthcare$205,702$99.040%
Chemicals$161,623$78.010%

Clinical Trial Project Management Manager, Sr. Salary: Hourly Rate, Weekly Pay, and Monthly Pay

Understanding how a Clinical Trial Project Management Manager, Sr.'s annual salary breaks down can help with budgeting. Below, you can see the average hourly rate, weekly pay, and monthly pay for this role. Use the buttons to switch between different pay periods.

  • Hourly
  • Monthly
  • Weekly
  • Yearly
  • Table View
Last Updated on August 01, 2026
$135,240
Average $146,930/year
$161,840
$11,270
Average $12,244/month
$13,487
$2,601
Average $2,826/week
$3,112
$65
Average $71/hour
$78
Annual Salary Monthly Pay Weekly Pay Hourly Wage
75th Percentile $161,840 $13,487 $3,112 $78
Average $146,930 $12,244 $2,826 $71
25th Percentile $135,240 $11,270 $2,601 $65

Clinical Trial Project Management Manager, Sr. Salary Growth & Career Path

Clinical Trial Project Management Manager, Sr.
Clinical Study Project Management Director
VP of Clinical Study Project Management

For a Clinical Trial Project Management Manager, Sr., the most direct path to higher earnings is advancing to the Clinical Study Project Management Director role. This promotion typically comes with a significant pay increase, bringing the average annual salary to $168,000 - a projected growth of 14% over your current level.

Salaries of jobs related to Clinical Trial Project Management Manager, Sr.

Most common benefits for Clinical Trial Project Management Manager, Sr.

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Common company salaries for Clinical Trial Project Management Manager, Sr.

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United States

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FAQ about Clinical Trial Project Management Manager, Sr.

1. What industry pays the highest salary for Clinical Trial Project Management Manager, Sr.?

The Healthcare industry offers the highest average compensation for Clinical Trial Project Management Manager, Sr. roles, with salaries approximately 40% above the market median.

2. What salary should I ask for project manager?

For a Clinical Trial Project Management Manager position, you should consider asking for a salary in the range of $174,250 to $208,540, with a midpoint of $188,390. This reflects the competitive nature of the role and aligns with industry standards for experienced professionals in this field.

3. How much does a clinical project manager make at Iqvia?

The salary for a Clinical Trial Project Management Manager, Sr. ranges from $174,250 to $208,540, with a midpoint of $188,390. This reflects the competitive compensation in the field, which may vary based on experience and location. Additional pay may also be available, enhancing overall earnings.

4. How much does a senior project manager make at Bank of America?

The estimated total pay range for a Senior Clinical Trial Project Management Manager is between $174,250 and $208,540 per year, reflecting the base salary and potential additional compensation. This range highlights the competitive nature of salaries in this specialized field.

5. How much do clinical trial managers make at Worldwide Clinical Trials?

Clinical Trial Project Management Managers at Worldwide Clinical Trials can expect a salary range from $174,250 to $208,540, with a midpoint of $188,390. This reflects the specialized nature of the role and the significant responsibilities involved in managing clinical trials.

6. How many years is a senior project manager?

A senior project manager usually holds a bachelor's degree in business, finance, or marketing and has five to 10 years of relevant experience. While not mandatory, many also possess backgrounds in software engineering or computer science. In terms of compensation, salaries for this role range from $174,250 to $208,540, with a median salary of $188,390.

7. What is the highest salary for a clinical trial manager?

The highest salary for a Clinical Trial Project Management Manager, Sr. is $208,540 annually. The salary range for this position typically starts at $174,250, with a mid-point of $188,390. This reflects the competitive compensation in the field, particularly for experienced professionals.

Where Does Our Salary Data Come From?

Salary.com provides salary estimates, histograms, trends, and comparisons using data from employer job postings and third-party sources.

We offer detailed salary information across multiple percentiles for your reference. (Click here to learn Why the Salary Midpoint Formula Is Crucial for Achieving Pay Equity.)

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