As of July 01, 2026, the average salary for a Clinical Research Associate I in Missouri is $58,279 per year, which breaks down to an hourly rate of $28.
However, a Clinical Research Associate I's salary can vary significantly. Here’s a look at the typical salary range:
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Clinical Research Associate I Salaries by Percentile
| Annual Salary |
Monthly Pay |
Weekly Pay |
Hourly Wage |
|
| 75th Percentile | $67,091 | $5,591 | $1,290 | $32 |
| Average | $58,279 | $4,857 | $1,121 | $28 |
| 25th Percentile | $50,075 | $4,173 | $963 | $24 |
ChenMed - Saint Louis, MO
ChenMed - Moline Acres, MO
ChenMed - Moline Acres, MO
ChenMed - Pasadena Park, MO
A Clinical Research Associate I's salary isn't a fixed number. It's shaped by several important factors. Below, we'll explore how your years of experience, geographic location, and company size can directly affect your earning potential.
Experience is a primary driver of a Clinical Research Associate I's salary. As you build your skills and take on more complex tasks, your compensation generally increases. Here's how the average salary grows at different career stages:
| Job Role | Years of Experience | Average Salary |
|---|---|---|
| Staff Nurse - RN - Research | 0-0 years | $90,069 |
| Clinical Research Associate I | 0-2 years | $58,279 |
| Clinical Research Associate II | 2-4 years | $67,441 |
| Scientist - Clinical Research | 4-7 years | $95,767 |
| Clinical Research Manager | 7+ years | $103,466 |
What Am I Worth?
Your salary can change significantly depending on where you work. States with a higher cost of living and strong industrial sectors often pay more to attract Clinical Research Associate Is. For example, consider the average annual salaries in these key locations:
Salaries can also vary between different cities. Major metropolitan areas or cities with a high demand for technicians often offer more competitive pay. Here are a few examples of average annual salaries in different U.S. cities:
Clinical Research Associate I salary potential scales significantly with company size. Data shows that Enterprise companies (5,000+ employees) pay the highest average salary at around $65,557. While startup companies pay approximate $55,666.
| Company Size | Employees | Average Salary |
|---|---|---|
| Startup | 1~50 | $55,666 |
| Growth Stage | 51~500 | $58,813 |
| Established | 501~5000 | $63,367 |
| Enterprise | 5000+ | $65,557 |
For Clinical Research Associate I roles, the industry you choose can affect earning potential by as much as 40% (the gap between the highest and lowest paying industries). Data shows that the Healthcare and Edu., Gov't. & Nonprofit sectors offer the strongest compensation, at 20% above the average. In contrast, Clinical Research Associate positions in Pharmaceuticals or Biotechnology typically offer lower base pay, as these industries often view Clinical Research Associate I as a support function rather than a direct revenue driver.
| Industry Sector | Average Annual Salary | Average Hourly Rate | Pay vs.Avg |
|---|---|---|---|
| Healthcare | $69,935 | $34.0 | 20% |
| Edu., Gov't. & Nonprofit | $64,107 | $31.0 | 10% |
Understanding how a Clinical Research Associate I's annual salary breaks down can help with budgeting. Below, you can see the average hourly rate, weekly pay, and monthly pay for this role. Use the buttons to switch between different pay periods.
| Annual Salary | Monthly Pay | Weekly Pay | Hourly Wage | |
|---|---|---|---|---|
| 75th Percentile | $67,091 | $5,591 | $1,290 | $32 |
| Average | $58,279 | $4,857 | $1,121 | $28 |
| 25th Percentile | $50,075 | $4,173 | $963 | $24 |
Promotions are the fastest way to increase your earnings. As a Clinical Research Associate I, you have the following paths for advancement. The table below compares the salary raises for common next-step roles. By comparing these figures, you can choose the career path that best meets your financial goals.
| Next Step Role | Estimate Salary | Projected Raise |
|---|---|---|
| Clinical Research Monitor II | $73,543 | 26% |
| Clinical Research Associate II | $67,441 | 16% |
Ready to take the next step in your career? Browse thousands of current Clinical Research Associate I job openings on our job board. Use the search bar below to find your perfect match.
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