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As of August 01, 2026, the average salary for a Clinical Trial Manager in California is $120,327 per year, which breaks down to an hourly rate of $58.
However, a Clinical Trial Manager's salary can vary significantly. Here’s a look at the typical salary range:
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Clinical Trial Manager Salaries by Percentile
| Annual Salary |
Monthly Pay |
Weekly Pay |
Hourly Wage |
|
| 75th Percentile | $130,428 | $10,869 | $2,508 | $63 |
| Average | $120,327 | $10,027 | $2,314 | $58 |
| 25th Percentile | $108,688 | $9,057 | $2,090 | $52 |
Janux Therapeutics - San Diego, CA
Soleno - Redwood City, CA
Imperative Care - Campbell, CA
Janux Therapeutics - San Diego, CA
A Clinical Trial Manager's salary isn't a fixed number. It's shaped by several important factors. Below, we'll explore how your years of experience, geographic location and company size can directly affect your earning potential.
Experience is a primary driver of a Clinical Trial Manager's salary. As you build your skills and take on more complex tasks, your compensation generally increases. Here’s how the average salary grows at different career stages:
| Levels | Salary |
|---|---|
| Clinical ... Level Clinical Trial Manager | $77,948 |
| Scientist... Level Clinical Trial Manager | $110,699 |
| Clinical ... Level Clinical Trial Manager | $119,585 |
| Clinical ... Level Clinical Trial Manager | $178,037 |
| VP of Cli... Level Clinical Trial Manager | $274,576 |
What Am I Worth?
Your salary can change significantly depending on where you work. States with a higher cost of living and strong industrial sectors often pay more to attract Clinical Trial Managers. For example, consider the average annual salaries in these key locations:
Salaries can also vary between different cities. Major metropolitan areas or cities with a high demand for technicians often offer more competitive pay. Here are a few examples of average annual salaries in different U.S. cities:
For Clinical Trial Manager roles, the industry you choose can affect earning potential by as much as 60% (the gap between the highest and lowest paying industries). Data shows that the MFG Durable and Biotechnology sectors offer the strongest compensation, at 30% above the average. In contrast, Clinical Trial Manager positions in MFG Nondurable or Business Services typically offer lower base pay, as these industries often view Clinical Trial Manager as a support function rather than a direct revenue driver.
| Industry Sector | Average Annual Salary | Average Hourly Rate | Pay vs.Avg |
|---|---|---|---|
| MFG Durable | $156,426 | $75.0 | 30% |
| Biotechnology | $144,393 | $69.0 | 20% |
| Edu., Gov't. & Nonprofit | $132,360 | $64.0 | 10% |
Understanding how a Clinical Trial Manager's annual salary breaks down can help with budgeting. Below, you can see the average hourly rate, weekly pay, and monthly pay for this role. Use the buttons to switch between different pay periods.
| Annual Salary | Monthly Pay | Weekly Pay | Hourly Wage | |
|---|---|---|---|---|
| 75th Percentile | $130,428 | $10,869 | $2,508 | $63 |
| Average | $120,327 | $10,027 | $2,314 | $58 |
| 25th Percentile | $108,688 | $9,057 | $2,090 | $52 |
Ready to take the next step in your career? Browse thousands of current Clinical Trial Manager job openings on our job board. Use the search bar below to find your perfect match.
MyOme
San Francisco, CA
MyOme | San Francisco, CA
Job Description. Job Description. MyOme's mission is to provide clinically actionable genetic information to patients throughout their lives. We combine cl... more
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Job Description. Job Description. Company Description. Zai Lab Limited (NASDAQ: ZLAB. HKEX: 9688) is an innovative, research-based, commercial-stage biopha... more
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BLOSSOMHILL THERAPEUTICS INC
San Diego, CA
BLOSSOMHILL THERAPEUTICS INC | San Diego, CA
Job Description. Job Description. About BlossomHill Therapeutics. BlossomHill Therapeutics, Inc. is a clinical-stage biopharmaceutical company applying an ... more
7 Days Ago
Maze Therapeutics
South San Francisco, CA
Maze Therapeutics | South San Francisco, CA
Job Description. Job Description. The Opportunity. At Maze Therapeutics, we believe that precision medicine has the power to transform the lives of patient... more
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Neurocentria
Walnut Creek, CA
Neurocentria | Walnut Creek, CA
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REVOLUTION Medicines
Redwood City, CA
REVOLUTION Medicines | Redwood City, CA
Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addic... more
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