Clinical Trial Manager Salary in South Carolina

How much does a Clinical Trial Manager make in South Carolina?

As of August 01, 2026, the average salary for a Clinical Trial Manager in South Carolina is $102,218 per year, which breaks down to an hourly rate of $49.

However, a Clinical Trial Manager's salary can vary significantly. Here’s a look at the typical salary range:

  • Top Earners (90th percentile): $118,610
  • Majority Range (25th-75th percentile): $92,331 to $110,798
  • Entry-Level (10th percentile): $83,328
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View as table View as graph 25% $92,331 10% $83,328 90% $118,610 75% $110,798 $102,218 50%(Median) Didn’t find job title? Click

Clinical Trial Manager Salaries by Percentile

Annual
Salary
Monthly
Pay
Weekly
Pay
Hourly
Wage
75th Percentile $110,798 $9,233 $2,131 $53
Average $102,218 $8,518 $1,966 $49
25th Percentile $92,331 $7,694 $1,776 $44
Check out Clinical Trial Manager Job Openings in South Carolina
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Clemson Eye - Greenville, SC

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United Energy Workers Healthcare - Aiken, SC

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Carolinas Centers for Sight - Hartsville, SC

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Key Factors That Influence Clinical Trial Manager Salaries

A Clinical Trial Manager's salary isn't a fixed number. It's shaped by several important factors. Below, we'll explore how your years of experience, geographic location and company size can directly affect your earning potential.

How Experience Level Affects Clinical Trial Manager Salaries?

Experience is a primary driver of a Clinical Trial Manager's salary. As you build your skills and take on more complex tasks, your compensation generally increases. Here’s how the average salary grows at different career stages:

  • Entry-Level (less than 1 year): $66,217
  • Early Career (1-2 years): $94,039
  • Mid-Level (2-4 years): $101,588
  • Senior-Level (5-8 years): $151,243
  • Expert (over 8 years): $233,253
Levels Salary
Clinical ... Level Clinical Trial Manager$66,217
Scientist... Level Clinical Trial Manager$94,039
Clinical ... Level Clinical Trial Manager$101,588
Clinical ... Level Clinical Trial Manager$151,243
VP of Cli... Level Clinical Trial Manager$233,253
$66,217 0 yr
$94,039 < 2 yrs
$101,588 2-4 yrs
$151,243 5-8 yrs
$233,253 > 8 yrs
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What Am I Worth?

Top Paying Cities for Clinical Trial Managers

Salaries can also vary between different cities. Major metropolitan areas or cities with a high demand for technicians often offer more competitive pay. Here are a few examples of average annual salaries in different U.S. cities:

  • Spartanburg: $101,847
  • Boiling Springs: $101,852
  • Arcadia: $101,847

Clinical Trial Manager Salary by Industry: Top Paying Sectors

For Clinical Trial Manager roles, the industry you choose can affect earning potential by as much as 60% (the gap between the highest and lowest paying industries). Data shows that the MFG Durable and Biotechnology sectors offer the strongest compensation, at 30% above the average. In contrast, Clinical Trial Manager positions in MFG Nondurable or Business Services typically offer lower base pay, as these industries often view Clinical Trial Manager as a support function rather than a direct revenue driver.

The top paying industries for a Clinical Trial Manager

Industry Sector Average Annual Salary Average Hourly Rate Pay vs.Avg
MFG Durable$132,884$64.030%
Biotechnology$122,662$59.020%
Edu., Gov't. & Nonprofit$112,440$54.010%

Clinical Trial Manager Salary: Hourly Rate, Weekly Pay, and Monthly Pay

Understanding how a Clinical Trial Manager's annual salary breaks down can help with budgeting. Below, you can see the average hourly rate, weekly pay, and monthly pay for this role. Use the buttons to switch between different pay periods.

Last Updated on August 01, 2026

Find Your Next Clinical Trial Manager Job

Ready to take the next step in your career? Browse thousands of current Clinical Trial Manager job openings on our job board. Use the search bar below to find your perfect match.

United States
  • Outset Medical

    Charleston, SC

    Outset Medical | Charleston, SC

    Clinical Excellence Manager. Join us for an enriching journey with Outset, a trailblazing medical device company that is revolutionizing the field of dialy... more

    1 Day Ago

  • Stanton Optical

    Conway, SC

    Stanton Optical | Conway, SC

    Job Description. Job Description. Clinical Services Manager. Reports to. Brand Manager. Location. On-site store location. Do you have a passion to train an... more

    2 Days Ago

  • Stanton Optical

    Lexington, SC

    Stanton Optical | Lexington, SC

    Job Description. Job Description. Clinical Services Manager. Reports to. Brand Manager. Location. On-site store location. Do you have a passion to train an... more

    2 Days Ago

  • K.A. Recruiting

    Graniteville, SC

    K.A. Recruiting | Graniteville, SC

    Clinical Nurse Manager. A growing healthcare organization is seeking an experienced Clinical Nurse Manager to oversee operations across two free-standing e... more

    2 Days Ago

  • BrightSpring Health Services

    Rock Hill, SC

    BrightSpring Health Services | Rock Hill, SC

    Home Health Clinical Manager. Adoration Home Health is seeking a passionate, dedicated Home Health RN Clinical Manager to join our team in Rock Hill, SC. I... more

    4 Days Ago

  • PAREXEL

    Columbia, SC

    PAREXEL | Columbia, SC

    Works with Precision Medicine Strategy Lead as well as clinical study teams, data management (DM) team, Samples, Kits, Data, Logistics (SKDL) and Clinical ... more

    5 Days Ago

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