How much does an Emergency Room Nurse make in San Diego, CA? The average Emergency Room Nurse salary in San Diego, CA is $85,445 as of April 01, 2025, but the salary range typically falls between $76,543 and $95,432. Salary ranges can vary widely depending on many important factors, including education, certifications, additional skills, the number of years you have spent in your profession. With more online, real-time compensation data than any other website, Salary.com helps you determine your exact pay target.
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