Senior Bioinformatician Salary in the United States

How much does a Senior Bioinformatician make in the United States?

As of July 01, 2026, the average salary for a Senior Bioinformatician in the United States is $107,211 per year, which breaks down to an hourly rate of $52.

However, a Senior Bioinformatician's salary can vary significantly. Here’s a look at the typical salary range:

  • Top Earners (90th percentile): $121,620
  • Majority Range (25th-75th percentile): $97,344 to $114,753
  • Entry-Level (10th percentile): $88,361
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View as table View as graph 25% $97,344 10% $88,361 90% $121,620 75% $114,753 $107,211 50%(Median) Didn’t find job title? Click

Senior Bioinformatician Salaries by Percentile

Annual
Salary
Monthly
Pay
Weekly
Pay
Hourly
Wage
75th Percentile $114,753 $9,563 $2,207 $55
Average $107,211 $8,934 $2,062 $52
25th Percentile $97,344 $8,112 $1,872 $47
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Key Factors That Influence Senior Bioinformatician Salaries

A Senior Bioinformatician's salary isn't a fixed number. It's shaped by several important factors. Below, we'll explore how your years of experience, geographic location, education and company size can directly affect your earning potential.

Top Paying Cities for Senior Bioinformaticians

Salaries can also vary between different cities. Major metropolitan areas or cities with a high demand for technicians often offer more competitive pay. Here are a few examples of average annual salaries in different U.S. cities:

  • San Jose: $135,225
  • San Francisco: $133,745
  • Oakland: $130,926

What Skills Can Increase a Senior Bioinformatician's Salary?

Demanded Skills for the Role:

  • Analysis (Mentioned in 20.51% Job Postings): Analysis is the process of considering something carefully or using statistical methods in order to understand it or explain it.
  • Python (Mentioned in 3.35% Job Postings): Applying the concepts and algorithms of Python to design, develop and maintain software applications to comply with business requirements.
  • Molecular Biology (Mentioned in 1.31% Job Postings): Molecular biology /məˈlɛkjʊlər/ is a branch of biology that concerns the molecular basis of biological activity between biomolecules in the various systems of a cell, including the interactions between DNA, RNA, proteins and their biosynthesis, as well as the regulation of these interactions. Writing in Nature in 1961, William Astbury described molecular biology as:
See More Skills
Skills Demand Percentage
Analysis 20.51%
Python 3.35%
Molecular Biology 1.31%
What skills can make your compensation higher?
Mastering certain specialized skills can lead to a significant increase in pay. Here are examples of skills and the potential impact they can have on a Senior Bioinformatician's salary.
  • Molecular Biology: Can increase your salary by up to 7%.
  • Organizing: Can increase your salary by up to 7%.
  • Alignment: Can increase your salary by up to 5%.
Skill Salary Salary % Increase
Molecular Biology
$114,716
7%
Organizing
$114,716
7%
Alignment
$112,572
5%
Innovation
$111,499
4%
Oral Communication
$111,499
4%
Data Management
$111,499
4%
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Senior Bioinformatician Salary by Industry: Top Paying Sectors

For Senior Bioinformatician roles, the industry you choose can affect earning potential by as much as 40% (the gap between the highest and lowest paying industries). Data shows that the Biotechnology and Healthcare sectors offer the strongest compensation, at 20% above the average. In contrast, Senior Bioinformatician positions in Edu., Gov't. & Nonprofit or MFG Nondurable typically offer lower base pay, as these industries often view Senior Bioinformatician as a support function rather than a direct revenue driver.

The top paying industries for a Senior Bioinformatician

Industry Sector Average Annual Salary Average Hourly Rate Pay vs.Avg
Biotechnology$128,653$62.020%
Healthcare$117,932$57.010%

How Education impacts a Senior Bioinformatician's Salary?

Your level of education can impact your salary potential. While many Senior Bioinformaticians enter the field with a Associate's Degree degree, higher education can lead to more specialized and higher-paying roles.

According to our 100% employer-reported salary data, the median salary for a Senior Bioinformatician with a Associate's Degree is between $106,145 and $111,595).

Senior Bioinformatician Salaries by Degree Level

Typical Education for Senior Bioinformatician
Degree Level % of user with this level of education
No Diploma 21.6%
High School 78.4%
Associates 0.0%
Bachelors 21.6%
Masters 78.4%
Doctorate 0.0%
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Senior Bioinformatician Salary: Hourly Rate, Weekly Pay, and Monthly Pay

Understanding how a Senior Bioinformatician's annual salary breaks down can help with budgeting. Below, you can see the average hourly rate, weekly pay, and monthly pay for this role. Use the buttons to switch between different pay periods.

Last Updated on July 01, 2026

Salary Trends for Senior Bioinformatician

Salaries for a Senior Bioinformatician can change over time, reflecting shifts in market demand and the overall economy. The median salary decreased from $104,708 in 2023 to around $104,001 in 2025, reflecting changes in demand, location, experience, and the wider economy. For a detailed analysis of Senior Bioinformatician salary trends, .

Average Annual Salary of Senior Bioinformatician Over Time

2022
$???
2023
$104,708
2024
$104,482
2025
$104,001
2026
$???
2027
$???
Year Average Annual Salary
2022
View More
2023 $104,708
2024 $104,482
2025 $104,001
2026
View More
2027
View More

Most common benefits for Senior Bioinformatician

Social Security
401(k)
Disability
Healthcare
Pension
Time Off (days)
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Common company salaries for Senior Bioinformatician

Here are companies hiring for Senior Bioinformatician and their salaries, click below for more details.

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Where Does Our Salary Data Come From?

Salary.com provides salary estimates, histograms, trends, and comparisons using data from employer job postings and third-party sources.

We offer detailed salary information across multiple percentiles for your reference. (Click here to learn Why the Salary Midpoint Formula Is Crucial for Achieving Pay Equity.)

With the most extensive online, real-time compensation data available, Salary.com helps you pinpoint your exact pay target.

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