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As of August 01, 2026, the average salary for an Emergency Nurse Practitioner in Missouri is $127,509 per year, which breaks down to an hourly rate of $61.
However, an Emergency Nurse Practitioner's salary can vary significantly. Here’s a look at the typical salary range:
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Emergency Nurse Practitioner Salaries by Percentile
| Annual Salary |
Monthly Pay |
Weekly Pay |
Hourly Wage |
|
| 75th Percentile | $135,022 | $11,252 | $2,597 | $65 |
| Average | $127,509 | $10,626 | $2,452 | $61 |
| 25th Percentile | $120,100 | $10,008 | $2,310 | $58 |
University of Missouri School of Medicine - Columbia, MO
Amergis Locum Tenens - Saint Louis, MO
ICON Medical Network - West Plains, MO
SSM Health - St Louis, MO
An Emergency Nurse Practitioner's salary isn't a fixed number. It's shaped by several important factors. Below, we'll explore how your years of experience, geographic location and company size can directly affect your earning potential.
Experience is a primary driver of an Emergency Nurse Practitioner's salary. As you build your skills and take on more complex tasks, your compensation generally increases. Here’s how the average salary grows at different career stages:
| Levels | Salary |
|---|---|
| Entry Level Emergency Nurse Practitioner | $125,760 |
| Intermediate Level Emergency Nurse Practitioner | $125,965 |
| Senior Level Emergency Nurse Practitioner | $126,789 |
| Specialist Level Emergency Nurse Practitioner | $128,024 |
| Expert Level Emergency Nurse Practitioner | $130,678 |
What Am I Worth?
Your salary can change significantly depending on where you work. States with a higher cost of living and strong industrial sectors often pay more to attract Emergency Nurse Practitioners. For example, consider the average annual salaries in these key locations:
Salaries can also vary between different cities. Major metropolitan areas or cities with a high demand for technicians often offer more competitive pay. Here are a few examples of average annual salaries in different U.S. cities:
For Emergency Nurse Practitioner roles, the industry you choose can impact your earning potential by as much as 20% (the gap between the highest and lowest paying industries). Data shows that the highest-paying industry, Healthcare, offers compensation 10% above the average. Conversely, Emergency Nurse Practitioner positions in Edu., Gov't. & Nonprofit typically offer lower base pay, as this sector often view Emergency Nurse Practitioner as a support function rather than a direct revenue driver.
| Industry Sector | Average Annual Salary | Average Hourly Rate | Pay vs.Avg |
|---|---|---|---|
| Healthcare | $140,260 | $67.0 | 10% |
Understanding how an Emergency Nurse Practitioner's annual salary breaks down can help with budgeting. Below, you can see the average hourly rate, weekly pay, and monthly pay for this role. Use the buttons to switch between different pay periods.
| Annual Salary | Monthly Pay | Weekly Pay | Hourly Wage | |
|---|---|---|---|---|
| 75th Percentile | $135,022 | $11,252 | $2,597 | $65 |
| Average | $127,509 | $10,626 | $2,452 | $61 |
| 25th Percentile | $120,100 | $10,008 | $2,310 | $58 |
Ready to take the next step in your career? Browse thousands of current Emergency Nurse Practitioner job openings on our job board. Use the search bar below to find your perfect match.
RecruitWell
Independence, MO
RecruitWell | Independence, MO
Locums Emergency Medicine NP/PA - Independence, Missouri Availability. Projected Start Date: October 23, 2026 (earlier start preferred if available). Assig... more
17 Days Ago
Solomon Page
Potosi, MO
Solomon Page | Potosi, MO
The hospital is looking for an Emergency Medicine Nurse Practitioner to help out with as much coverage as possible from January 2026. Must have Emergency M... more
17 Days Ago
Amergis Locum Tenens
St Louis, MO
Amergis Locum Tenens | St Louis, MO
A local hospital in Alton, IL located in the St. Louis, Missouri area is in need of a locums emergency medicine APP. Alton, Illinois, is a charming city lo... more
17 Days Ago
Palm Health Resources
Washington, MO
Palm Health Resources | Washington, MO
We are hiring a LOCUM TENEN Nurse Practitioner or Physician Assistant for our Critical Care ICU need near Saint Louis, Missouri. The assignment is looking ... more
17 Days Ago
Ascend Medical Staffing
Perryville, MO
Ascend Medical Staffing | Perryville, MO
Location: Perryville, MO Hospital: Mercy Hospital Perry Start Date: November 1, 2024 End Date: Ongoing Mercy Hospital Perry is looking for a ARNP with Emer... more
17 Days Ago
Community Health Systems
Poplar Bluff, MO
Community Health Systems | Poplar Bluff, MO
Poplar Bluff Regional Medical Center is seeking an experienced Emergency Medicine Nurse Practitioner to join its Emergency Department team in Poplar Bluff,... more
17 Days Ago
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