As of May 01, 2026, the average annual salary for Senior Bioinformatics Scientist in the US is $127,140, equivalent to $61 per hour, $2,445 weekly, or $10,595 monthly. These figures, sourced from Salary.com’s real-time job posting scans, highlight competitive earning potential for Senior Bioinformatics Scientist in cities like San Jose, Santa Clara, and San Francisco.
Annually Salaries for Senior Bioinformatics Scientist in the US vary widely, spanning from $116,357 to $139,809. Most professionals fall between the 25th percentile ($121,496) and 75th percentile ($133,771), while top earners (90th percentile) make $139,809 per year. This $12,275 pay gap underscores opportunities for salary growth through certifications, specialized skills like Analysis or SOP, or targeting high-paying regions like District of Columbia or California.
Location and experience significantly influence earnings. For example, District of Columbia Senior Bioinformatics Scientist often earn 10.7% above national averages due to demand from Fortune 73 companies and industry startups. Professionals are advised to focus on high-growth sectors like to offset market challenges.
