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Clinical Information Systems Manager Salary in South Carolina

How much does a Clinical Information Systems Manager make in South Carolina?

As of August 01, 2026, the average salary for a Clinical Information Systems Manager in South Carolina is $130,400 per year, which breaks down to an hourly rate of $63.

However, a Clinical Information Systems Manager's salary can vary significantly. Here’s a look at the typical salary range:

  • Top Earners (90th percentile): $157,719
  • Majority Range (25th-75th percentile): $120,100 to $144,700
  • Entry-Level (10th percentile): $110,722
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View as table View as graph 25% $120,100 10% $110,722 90% $157,719 75% $144,700 $130,400 50%(Median) Didn’t find job title? Click

Clinical Information Systems Manager Salaries by Percentile

Annual
Salary		 Monthly
Pay		 Weekly
Pay		 Hourly
Wage
75th Percentile $144,700 $12,058 $2,783 $70
Average $130,400 $10,867 $2,508 $63
25th Percentile $120,100 $10,008 $2,310 $58
Check out Clinical Information Systems Manager Job Openings in South Carolina
Information Systems Specialist

Cliffs Club Services, LLC - Travelers Rest, SC

Information Systems Technician

U.S. Navy - Varnville, SC

Information Systems Technician

U.S. Navy - Westminster, SC

Information Systems Technician

U.S. Navy - Whitmire, SC

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Key Factors That Influence Clinical Information Systems Manager Salaries

A Clinical Information Systems Manager's salary isn't a fixed number. It's shaped by several important factors. Below, we'll explore how your years of experience, geographic location, and company size can directly affect your earning potential.

How Experience Level Affects Clinical Information Systems Manager Salaries?

Experience is a primary driver of a Clinical Information Systems Manager's salary. As you build your skills and take on more complex tasks, your compensation generally increases. Here's how the average salary grows at different career stages:

  • Clinical Information Coordinator II (2-4 years): $86,348
  • Health Informatics Specialist III (4-7 years): $104,326
  • Clinical Information Systems Manager (7+ years): $130,341
  • Clinical Information Systems Senior Manager (7+ years): $146,074
  • Clinical Information Systems Director (7+ years): $161,714
Job Role Years of Experience Average Salary
Clinical Information Coordinator II2-4 years$86,348
Health Informatics Specialist III4-7 years$104,326
Clinical Information Systems Manager7+ years$130,341
Clinical Information Systems Senior Manager7+ years$146,074
Clinical Information Systems Director7+ years$161,714
$86,348 Clinical ...
$104,326 Health In...
$130,341 Clinical ...
$146,074 Clinical ...
$161,714 Clinical ...
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What Am I Worth?

Top Paying Cities for Clinical Information Systems Managers

Salaries can also vary between different cities. Major metropolitan areas or cities with a high demand for technicians often offer more competitive pay. Here are a few examples of average annual salaries in different U.S. cities:

  • Spartanburg: $129,900
  • Boiling Springs: $129,900
  • Arcadia: $129,900

Clinical Information Systems Manager Salary by Company Size: Startups vs. Enterprise

Clinical Information Systems Manager salary potential scales significantly with company size. Data shows that Enterprise companies (5,000+ employees) pay the highest average salary at around $146,731. While startup companies pay approximate $124,628.

Clinical Information Systems Manager Salary by Company Size

Company Size Employees Average Salary
Startup1~50$124,628
Growth Stage51~500$131,667
Established501~5000$141,822
Enterprise5000+$146,731

Clinical Information Systems Manager Salary by Industry: Top Paying Sectors

For Clinical Information Systems Manager roles, the industry you choose can affect earning potential by as much as 100% (the gap between the highest and lowest paying industries). Data shows that the Healthcare and Edu., Gov't. & Nonprofit sectors offer the strongest compensation, at 50% above the average. In contrast, Clinical Information Systems Manager positions in Pharmaceuticals or Biotechnology typically offer lower base pay, as these industries often view Clinical Information Systems Manager as a support function rather than a direct revenue driver.

The top paying industries for a Clinical Information Systems Manager

Industry Sector Average Annual Salary Average Hourly Rate Pay vs.Avg
Healthcare$195,600$94.050%
Edu., Gov't. & Nonprofit$143,440$69.010%

Clinical Information Systems Manager Salary: Hourly Rate, Weekly Pay, and Monthly Pay

Understanding how a Clinical Information Systems Manager's annual salary breaks down can help with budgeting. Below, you can see the average hourly rate, weekly pay, and monthly pay for this role. Use the buttons to switch between different pay periods.

  • Yearly
  • Monthly
  • Weekly
  • Hourly
  • Table View
Last Updated on August 01, 2026
$120,100
Average $130,400/year
$144,700
$10,008
Average $10,867/month
$12,058
$2,310
Average $2,508/week
$2,783
$58
Average $63/hour
$70
Annual Salary Monthly Pay Weekly Pay Hourly Wage
75th Percentile $144,700 $12,058 $2,783 $70
Average $130,400 $10,867 $2,508 $63
25th Percentile $120,100 $10,008 $2,310 $58

Clinical Information Systems Manager Salary Growth & Career Path

Clinical Information Systems Manager
Clinical Information Systems Senior Manager
Head of Clinical Information Systems

For a Clinical Information Systems Manager, the most direct path to higher earnings is advancing to the Clinical Information Systems Senior Manager role. This promotion typically comes with a significant pay increase, bringing the average annual salary to $146,100 - a projected growth of 12% over your current level.

Salaries of jobs related to Clinical Information Systems Manager

Find Your Next Clinical Information Systems Manager Job

Ready to take the next step in your career? Browse thousands of current Clinical Information Systems Manager job openings on our job board. Use the search bar below to find your perfect match.

United States

  • U.S. Navy

    Charleston, SC

    Information Systems Technician

    U.S. Navy | Charleston, SC

    Job Title :Information Technology Professional (IT/CTN/IS) Category / Component :Enlisted Both Overview Information Systems Technicians, Cryptologic Techni... more

    5 Days Ago

  • Geodesicx Inc

    North Charleston, SC

    Information Systems Security Officer

    Geodesicx Inc | North Charleston, SC

    Job Description. Job Description. Geodesicx is looking for an Information Systems Security Officer to join our team in the Charleston, SC area. Summary. Th... more

    2 Days Ago

  • SCS Tech

    Columbia, SC

    Information Systems Architect

    SCS Tech | Columbia, SC

    Hi Candidates, I've a below position, if you're qualified then share resume to vikas@scstech.us ASAP.Job Title:Information Systems Architect - Consultant C... more

    5 Days Ago

  • Jefferson Community College

    WATERTOWN, NY

    Programmer Information Systems Specialist

    Jefferson Community College | WATERTOWN, NY

    Jefferson Community College Watertown, New York Programmer/Information Systems Specialist Jefferson Community College, Watertown, New York, a member of the... more

    1 Day Ago

  • Adventist Health

    RIO VISTA, CA

    Manager Health Information Management

    Adventist Health | RIO VISTA, CA

    Adventist Health seeks a Manager, Health Information Management to lead daily HIM operations, including medical record integrity, coding, release of inform... more

    4 Days Ago

  • Adventist Health

    LINDEN, CA

    Manager Health Information Management

    Adventist Health | LINDEN, CA

    Adventist Health seeks a Manager, Health Information Management to lead daily HIM operations, including medical record integrity, coding, release of inform... more

    4 Days Ago

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