As of July 01, 2026, the average salary for a Clinical Operation Manager in the United States is $74,039 per year, which breaks down to an hourly rate of $36.
However, a Clinical Operation Manager's salary can vary significantly. Here’s a look at the typical salary range:
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A Clinical Operation Manager's salary isn't a fixed number. It's shaped by several important factors. Below, we'll explore how your years of experience, geographic location, education and company size can directly affect your earning potential.
Your salary can change significantly depending on where you work. States with a higher cost of living and strong industrial sectors often pay more to attract Clinical Operation Managers. For example, consider the average annual salaries in these key locations:
Demanded Skills for the Role:
| Skills | Demand Percentage |
|---|---|
| Leadership | 10.17% |
| Clinical Operations | 2.17% |
| Continuous Quality Improvement | 1.61% |
| Skill | Salary | Salary % Increase |
|---|---|---|
|
Clinical Trial
|
$79,962 |
8%
|
|
Clinical Research
|
$78,482 |
6%
|
|
Commitment
|
$77,741 |
5%
|
|
Accountability
|
$77,001 |
4%
|
|
Confidentiality
|
$77,001 |
4%
|
|
Project Management
|
$76,260 |
3%
|
For Clinical Operation Manager roles, the industry you choose can impact your earning potential by as much as 20% (the gap between the highest and lowest paying industries). Data shows that the highest-paying industry, Healthcare, offers compensation 10% above the average. Conversely, Clinical Operation Manager positions in Edu., Government & Nonprofit typically offer lower base pay, as this sector often view Clinical Operation Manager as a support function rather than a direct revenue driver.
| Industry Sector | Average Annual Salary | Average Hourly Rate | Pay vs.Avg |
|---|---|---|---|
| Healthcare | $81,443 | $39.0 | 10% |
Your level of education can impact your salary potential. While many Clinical Operation Managers enter the field with a High School Diploma or Technical Certificate degree, higher education can lead to more specialized and higher-paying roles.
According to our 100% employer-reported salary data, the median salary for a Clinical Operation Manager with a High School Diploma or Technical Certificate is between $74,771 and $81,097).
Clinical Operation Manager Salaries by Degree Level
| Degree Level | % of user with this level of education |
|---|---|
| No Diploma | 0.8% |
| High School | 26.2% |
| Associates | 15.3% |
| Bachelors | 34.4% |
| Masters | 20.9% |
| Doctorate | 2.4% |
Understanding how a Clinical Operation Manager's annual salary breaks down can help with budgeting. Below, you can see the average hourly rate, weekly pay, and monthly pay for this role. Use the buttons to switch between different pay periods.
Last Updated on July 01, 2026Salaries for a Clinical Operation Manager can change over time, reflecting shifts in market demand and the overall economy. The median salary decreased from $77,055 in 2023 to around $75,997 in 2025, reflecting changes in demand, location, experience, and the wider economy. For a detailed analysis of Clinical Operation Manager salary trends, .
| Year | Average Annual Salary |
|---|---|
| 2022 |
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|
| 2023 | $77,055 |
| 2024 | $77,105 |
| 2025 | $75,997 |
| 2026 |
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|
| 2027 |
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|
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