Know your market value with insights across roles — from individual contributors to executive pay and overall company compensation trends.
Access a suite of powerful calculators to make data-driven career decisions.
Automate pay cycles, manage job architectures, and ensure pay equity with AI-powered compensation platforms.
Access validated salary benchmarks, labor market trends, and minimum wage data to stay competitive.
Participate in and purchase industry-specific salary surveys to obtain the most accurate, peer-reported pay data.
As of August 01, 2026, the average salary for a Clinical Research Operations Manager in Iowa is $104,233 per year, which breaks down to an hourly rate of $50.
However, a Clinical Research Operations Manager's salary can vary significantly. Here’s a look at the typical salary range:
Compensation Planning
Develop a Job Description
Pay Equity
2026 Compensation Trend
AI-Powered Talent
AI Onboarding
Clinical Research Operations Manager Salaries by Percentile
| Annual Salary |
Monthly Pay |
Weekly Pay |
Hourly Wage |
|
| 75th Percentile | $112,582 | $9,382 | $2,165 | $54 |
| Average | $104,233 | $8,686 | $2,004 | $50 |
| 25th Percentile | $92,937 | $7,745 | $1,787 | $45 |
Outcomes Operating, Inc. - West Des Moines, IA
Outcomes Operating, Inc. - West Des Moines, IA
Jaybird Senior Living - Des Moines, IA
Family Medicine of Mount Pleasant P.C. - Mount Pleasant, IA
A Clinical Research Operations Manager's salary isn't a fixed number. It's shaped by several important factors. Below, we'll explore how your years of experience, geographic location and company size can directly affect your earning potential.
Experience is a primary driver of a Clinical Research Operations Manager's salary. As you build your skills and take on more complex tasks, your compensation generally increases. Here’s how the average salary grows at different career stages:
| Levels | Salary |
|---|---|
| Clinical ... Level Clinical Research Operations Manager | $68,452 |
| Scientist... Level Clinical Research Operations Manager | $97,213 |
| Clinical ... Level Clinical Research Operations Manager | $105,017 |
| Clinical ... Level Clinical Research Operations Manager | $156,348 |
| VP of Cli... Level Clinical Research Operations Manager | $241,127 |
What Am I Worth?
Your salary can change significantly depending on where you work. States with a higher cost of living and strong industrial sectors often pay more to attract Clinical Research Operations Managers. For example, consider the average annual salaries in these key locations:
Salaries can also vary between different cities. Major metropolitan areas or cities with a high demand for technicians often offer more competitive pay. Here are a few examples of average annual salaries in different U.S. cities:
For Clinical Research Operations Manager roles, the industry you choose can affect earning potential by as much as 60% (the gap between the highest and lowest paying industries). Data shows that the MFG Durable and Biotechnology sectors offer the strongest compensation, at 30% above the average. In contrast, Clinical Research Operations Manager positions in MFG Nondurable or Business Services typically offer lower base pay, as these industries often view Clinical Research Operations Manager as a support function rather than a direct revenue driver.
| Industry Sector | Average Annual Salary | Average Hourly Rate | Pay vs.Avg |
|---|---|---|---|
| MFG Durable | $135,502 | $65.0 | 30% |
| Biotechnology | $125,079 | $60.0 | 20% |
| Edu., Gov't. & Nonprofit | $114,656 | $55.0 | 10% |
Understanding how a Clinical Research Operations Manager's annual salary breaks down can help with budgeting. Below, you can see the average hourly rate, weekly pay, and monthly pay for this role. Use the buttons to switch between different pay periods.
| Annual Salary | Monthly Pay | Weekly Pay | Hourly Wage | |
|---|---|---|---|---|
| 75th Percentile | $112,582 | $9,382 | $2,165 | $54 |
| Average | $104,233 | $8,686 | $2,004 | $50 |
| 25th Percentile | $92,937 | $7,745 | $1,787 | $45 |
Ready to take the next step in your career? Browse thousands of current Clinical Research Operations Manager job openings on our job board. Use the search bar below to find your perfect match.
University of Iowa
Iowa City, IA
University of Iowa | Iowa City, IA
Clinical Pharmacist-Inpatient Pediatric Operations Pharmacist-Flexible Scheduling Available. The University of Iowa Healthcare Pediatric Department is seek... more
8 Days Ago
Jazz Pharmaceuticals
SHANNON PLAZA, NC
Jazz Pharmaceuticals | SHANNON PLAZA, NC
If you are a current Jazz employee please apply via the Internal Career site. Jazz Pharmaceuticals is a global biopharma company whose purpose is to innova... more
9 Days Ago
The LiRo Group
SYOSSET, NY
The LiRo Group | SYOSSET, NY
Project Manager (Academic Research) US-NY-Syosset Job ID: 2025-3070 of Openings: 1 Category: Construction Management The LiRo Group Overview We are seeking... more
5 Days Ago
ManTech International
TRIANGLE, VA
ManTech International | TRIANGLE, VA
ManTech International seeks an Operations Research Systems Analyst to support complex national security missions. You will apply operations research, stati... more
7 Days Ago
CSL Behring
WALTHAM, MA
CSL Behring | WALTHAM, MA
CSL Behring is seeking an Associate Director, Research Laboratory Operations to lead end-to-end lab operations supporting innovative plasma-derived and rec... more
5 Days Ago
Cone Health
SPRING VALLEY, NC
Cone Health | SPRING VALLEY, NC
Cone Health is seeking an RN Clinical Research Nurse to support oncology studies within our Scientific Research & Development department. In this role, you... more
8 Days Ago
Get a Salary Increase
Analyze the market and your qualifications to negotiate your salary with confidence.
Search Job Openings
Search thousands of open positions to find your next opportunity.
Adjust Employee Salary
Individualize employee pay based on unique job requirements and personal qualifications.
Price My Industry Jobs
Get the latest market price for benchmark jobs and jobs in your industry.
Use Salary.com's Cost of Living Calculator to find out what income you need to maintain your standard of living in a different city and how much more or less money you need to budget for basic expenses.
Explore Cost of Living CalculatorSalary.com experts will help you thrive your workplaces.
Salary.com provides salary survey data for thousands of industry Jobs.
Salary.com salary estimates, histograms, trends, and comparisons are derived from both employer job postings and third-party data sources. We also provide multiple percentiles of salary information for your reference, click here to know Why the Salary Midpoint Formula Is Crucial to Getting Pay Equity Right. With more online, real-time compensation data than any other website, Salary.com helps you determine your exact pay target.
Salary.com's CompAnalyst platform offers:
