What are the main factors that influence a Clinical Research Operations Manager's salary?

The primary factors are: 1) Experience Level, 2) Geographic Location, 3) Education/Skills, 4) Company Size & Industry

What industry pays the highest salary for Clinical Research Operations Manager?

The MFG Durable industry offers the highest average compensation for Clinical Research Operations Manager roles, with salaries approximately 30% above the market median.

How does experience change A Clinical Research Operations Manager's salary?

A Clinical Research Operations Manager's salary grows with experience: a Clinical Research Associate II (2-4 years)earns $79,198, a Scientist - Clinical Research (4-7 years)earns $112,462, a Clinical Research Operations Manager (7+ years)earns $121,503, a Clinical Research Director (7+ years)earns $180,898, a VP of Clinical Research (7+ years)earns $278,958,

What are the highest paying states for a Clinical Research Operations Manager?

Clinical Research Operations Manager salary varies significantly by state. The top 3 highest paying states for Clinical Research Operations Manager roles are District of Columbia $120,595, California $120,138, Massachusetts $118,537. These tech hubs typically pay 10-15% above the national average.

How much do different types of Clinical Research Operations Manager roles make?

Salaries for Clinical Research Operations Manager level roles vary by specialization: Operations Research Analysis Manager: $212,408; Research Operations Manager: $209,426; Clinical Research Project Management Manager, Sr.: $146,924; Clinical Research Onsite Monitoring Senior Manager: $143,080; Clinical Research Monitoring Senior Manager: $143,072.

Clinical Research Operations Manager Salary in District of Columbia

How much does a Clinical Research Operations Manager make in District of Columbia?

As of July 01, 2026, the average salary for a Clinical Research Operations Manager in District of Columbia is $120,595 per year, which breaks down to an hourly rate of $58.

However, a Clinical Research Operations Manager's salary can vary significantly. Here’s a look at the typical salary range:

Top Earners (90th percentile): $139,040
Majority Range (25th-75th percentile): $107,521 to $130,250
Entry-Level (10th percentile): $95,617

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Clinical Research Operations Manager Salaries by Percentile

	Annual Salary	Monthly Pay	Weekly Pay	Hourly Wage
75th Percentile	$130,250	$10,854	$2,505	$63
Average	$120,595	$10,050	$2,319	$58
25th Percentile	$107,521	$8,960	$2,068	$52

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Key Factors That Influence Clinical Research Operations Manager Salaries

A Clinical Research Operations Manager's salary isn't a fixed number. It's shaped by several important factors. Below, we'll explore how your years of experience, geographic location and company size can directly affect your earning potential.

How Experience Level Affects Clinical Research Operations Manager Salaries?

Experience is a primary driver of a Clinical Research Operations Manager's salary. As you build your skills and take on more complex tasks, your compensation generally increases. Here's how the average salary grows at different career stages:

Entry-Level (less than 1 year): $79,198
Early Career (1-2 years): $112,462
Mid-Level (2-4 years): $121,503
Senior-Level (5-8 years): $180,898
Expert (over 8 years): $278,958

Levels	Salary
Clinical ... Level Clinical Research Operations Manager	$79,198
Scientist... Level Clinical Research Operations Manager	$112,462
Clinical ... Level Clinical Research Operations Manager	$121,503
Clinical ... Level Clinical Research Operations Manager	$180,898
VP of Cli... Level Clinical Research Operations Manager	$278,958

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How Do Clinical Research Operations Manager Salaries Vary from State to State?

Your salary can change significantly depending on where you work. States with a higher cost of living and strong industrial sectors often pay more to attract Clinical Research Operations Managers. For example, consider the average annual salaries in these key locations:

District of Columbia: $120,595.
California: $120,138.
Massachusetts: $118,537.

District of Columbia $120,595 California $120,138 Massachusetts $118,537 Washington $118,101 New Jersey $118,057 Alaska $117,905 Connecticut $116,402 New York $115,792

Hawaii $113,842 Rhode Island $112,927 Maryland $112,306 Minnesota $111,457 Colorado $111,130 Illinois $111,021 Oregon $110,607 Delaware $110,302

New Hampshire $110,111 Virginia $109,681 Pennsylvania $108,429 Nevada $107,797 North Dakota $107,590 Michigan $107,263 Wisconsin $107,144 Vermont $106,904

Texas $106,240 Maine $106,196 Arizona $106,131 Ohio $106,054 Georgia $105,052 Indiana $104,551 Wyoming $104,453 Utah $104,301

Iowa $104,235 Kansas $103,713 Louisiana $103,560 North Carolina $103,506 Missouri $103,484 Florida $103,059 Montana $102,830 Nebraska $102,613

Kentucky $102,493 South Carolina $102,057 Tennessee $101,785 Idaho $101,676 New Mexico $100,881 Oklahoma $100,707 Alabama $100,064 South Dakota $98,986

Arkansas $98,397 West Virginia $98,082 Mississippi $97,134

Top Paying Cities for Clinical Research Operations Managers

Salaries can also vary between different cities. Major metropolitan areas or cities with a high demand for technicians often offer more competitive pay. Here are a few examples of average annual salaries in different U.S. cities:

Parcel Return Service: $119,941
Washington: $119,942
Naval Anacost Annex: $119,936

Parcel Return Service, DC $119,941 Washington, DC $119,942 Naval Anacost Annex, DC $119,936 Washington Navy Yard, DC $119,941

Clinical Research Operations Manager Salary by Industry: Top Paying Sectors

For Clinical Research Operations Manager roles, the industry you choose can affect earning potential by as much as 60% (the gap between the highest and lowest paying industries). Data shows that the MFG Durable and Biotechnology sectors offer the strongest compensation, at 30% above the average. In contrast, Clinical Research Operations Manager positions in MFG Nondurable or Business Services typically offer lower base pay, as these industries often view Clinical Research Operations Manager as a support function rather than a direct revenue driver.

The top paying industries for a Clinical Research Operations Manager

Industry Sector	Average Annual Salary	Average Hourly Rate	Pay vs.Avg
MFG Durable	$156,774	$75.0	30%
Biotechnology	$144,714	$70.0	20%
Edu., Gov't. & Nonprofit	$132,655	$64.0	10%

Clinical Research Operations Manager Salary: Hourly Rate, Weekly Pay, and Monthly Pay

Understanding how a Clinical Research Operations Manager's annual salary breaks down can help with budgeting. Below, you can see the average hourly rate, weekly pay, and monthly pay for this role. Use the buttons to switch between different pay periods.

Last Updated on July 01, 2026

$107,521

Average $120,595/year

$130,250

$8,960

Average $10,050/month

$10,854

$2,068

Average $2,319/week

$2,505

$52

Average $58/hour

$63

	Annual Salary	Monthly Pay	Weekly Pay	Hourly Wage
75th Percentile	$130,250	$10,854	$2,505	$63
Average	$120,595	$10,050	$2,319	$58
25th Percentile	$107,521	$8,960	$2,068	$52

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