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Clinical Research Operations Manager Salary in Pennsylvania

How much does a Clinical Research Operations Manager make in Pennsylvania?

As of August 01, 2026, the average salary for a Clinical Research Operations Manager in Pennsylvania is $108,426 per year, which breaks down to an hourly rate of $52.

However, a Clinical Research Operations Manager's salary can vary significantly. Here’s a look at the typical salary range:

  • Top Earners (90th percentile): $125,020
  • Majority Range (25th-75th percentile): $96,676 to $117,112
  • Entry-Level (10th percentile): $85,979
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Paid Annually Paid Monthly Paid Semimonthly Paid Biweekly Paid Weekly Paid Hourly
View as table View as graph 25% $96,676 10% $85,979 90% $125,020 75% $117,112 $108,426 50%(Median) Didn’t find job title? Click

Clinical Research Operations Manager Salaries by Percentile

Annual
Salary		 Monthly
Pay		 Weekly
Pay		 Hourly
Wage
75th Percentile $117,112 $9,759 $2,252 $56
Average $108,426 $9,035 $2,085 $52
25th Percentile $96,676 $8,056 $1,859 $46
Check out Clinical Research Operations Manager Job Openings in Pennsylvania
Manager Clinical Research Finance Operations

University of Pennsylvania - Philadelphia, PA

Manager Clinical Pharmacy Operations

Highmark Health - Monroeville, PA

Clinical Rehabilitation Operations Manager

HireNow Staffing - Narberth, PA

Clinical Research Project Manager

University of Pennsylvania - Philadelphia, PA

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Key Factors That Influence Clinical Research Operations Manager Salaries

A Clinical Research Operations Manager's salary isn't a fixed number. It's shaped by several important factors. Below, we'll explore how your years of experience, geographic location and company size can directly affect your earning potential.

How Experience Level Affects Clinical Research Operations Manager Salaries?

Experience is a primary driver of a Clinical Research Operations Manager's salary. As you build your skills and take on more complex tasks, your compensation generally increases. Here’s how the average salary grows at different career stages:

  • Entry-Level (less than 1 year): $71,206
  • Early Career (1-2 years): $101,124
  • Mid-Level (2-4 years): $109,242
  • Senior-Level (5-8 years): $162,638
  • Expert (over 8 years): $250,827
Levels Salary
Clinical ... Level Clinical Research Operations Manager$71,206
Scientist... Level Clinical Research Operations Manager$101,124
Clinical ... Level Clinical Research Operations Manager$109,242
Clinical ... Level Clinical Research Operations Manager$162,638
VP of Cli... Level Clinical Research Operations Manager$250,827
$71,206 0 yr
$101,124 < 2 yrs
$109,242 2-4 yrs
$162,638 5-8 yrs
$250,827 > 8 yrs
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What Am I Worth?

Top Paying Cities for Clinical Research Operations Managers

Salaries can also vary between different cities. Major metropolitan areas or cities with a high demand for technicians often offer more competitive pay. Here are a few examples of average annual salaries in different U.S. cities:

  • Beaver Meadows: $104,824
  • Coaldale: $105,644
  • Conyngham: $103,847

Clinical Research Operations Manager Salary by Industry: Top Paying Sectors

For Clinical Research Operations Manager roles, the industry you choose can affect earning potential by as much as 60% (the gap between the highest and lowest paying industries). Data shows that the MFG Durable and Biotechnology sectors offer the strongest compensation, at 30% above the average. In contrast, Clinical Research Operations Manager positions in MFG Nondurable or Business Services typically offer lower base pay, as these industries often view Clinical Research Operations Manager as a support function rather than a direct revenue driver.

The top paying industries for a Clinical Research Operations Manager

Industry Sector Average Annual Salary Average Hourly Rate Pay vs.Avg
MFG Durable$140,954$68.030%
Biotechnology$130,111$63.020%
Edu., Gov't. & Nonprofit$119,268$57.010%

Clinical Research Operations Manager Salary: Hourly Rate, Weekly Pay, and Monthly Pay

Understanding how a Clinical Research Operations Manager's annual salary breaks down can help with budgeting. Below, you can see the average hourly rate, weekly pay, and monthly pay for this role. Use the buttons to switch between different pay periods.

  • Yearly
  • Monthly
  • Weekly
  • Hourly
  • Table View
Last Updated on August 01, 2026
$96,676
Average $108,426/year
$117,112
$8,056
Average $9,035/month
$9,759
$1,859
Average $2,085/week
$2,252
$46
Average $52/hour
$56
Annual Salary Monthly Pay Weekly Pay Hourly Wage
75th Percentile $117,112 $9,759 $2,252 $56
Average $108,426 $9,035 $2,085 $52
25th Percentile $96,676 $8,056 $1,859 $46

Salaries of jobs related to Clinical Research Operations Manager

Find Your Next Clinical Research Operations Manager Job

Ready to take the next step in your career? Browse thousands of current Clinical Research Operations Manager job openings on our job board. Use the search bar below to find your perfect match.

United States

  • SOUTH COLLEGE

    Cranberry Township, PA

    Nursing Clinical Operations Specialist

    SOUTH COLLEGE | Cranberry Township, PA

    Job Description. Job Description. Description. Nursing Clinical Operations Specialist. Benefits. Front Loaded PTO. Tuition Assistance. Medical, Dental, Vis... more

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  • Valley West Health

    Johnstown, PA

    Regional Director of Clinical Operations

    Valley West Health | Johnstown, PA

    Job Description. Job Description. Serving Valley West Skilled Nursing Facilities – Pittsburgh and Altoona Region. Are you a seasoned clinical RN profession... more

    2 Days Ago

  • Valley West Health

    Waynesburg, PA

    Regional Director of Clinical Operations

    Valley West Health | Waynesburg, PA

    Job Description. Job Description. Serving Valley West Skilled Nursing Facilities – Pittsburgh and Altoona Region. Are you a seasoned clinical RN profession... more

    2 Days Ago

  • HNL Lab Medicine

    Allentown, PA

    Supervisor Clinical Laboratory Operations

    HNL Lab Medicine | Allentown, PA

    Job Posting. Work Schedule: Monday thru Friday, weekends and holidays as needed variable hours. Supervises and coordinates the activities of employees enga... more

    3 Days Ago

  • CSL Behring

    King Of Prussia, PA

    Director Clinical Operations Lead

    CSL Behring | King Of Prussia, PA

    CSL's R&D organization is accelerating innovation to deliver greater impact for patients. With a project-led structure and a focus on collaboration, we're ... more

    5 Days Ago

  • Confidential

    Philadelphia, PA

    Vice President Clinical Operations

    Confidential | Philadelphia, PA

    Vice President, Clinical Operations. About the Company. Innovative company designing & developing gene therapeutic products. Industry. Biotechnology. Type.... more

    19 Days Ago

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