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As of August 01, 2026, the average salary for a Practice Assistant in Missouri is $97,456 per year, which breaks down to an hourly rate of $47.
However, a Practice Assistant's salary can vary significantly. Here’s a look at the typical salary range:
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Practice Assistant Salaries by Percentile
| Annual Salary |
Monthly Pay |
Weekly Pay |
Hourly Wage |
|
| 75th Percentile | $106,450 | $8,871 | $2,047 | $51 |
| Average | $97,456 | $8,121 | $1,874 | $47 |
| 25th Percentile | $86,176 | $7,181 | $1,657 | $41 |
St. Louis South Oral Surgery - Saint Louis, MO
NextCare - Lees Summit, MO
University of Missouri School of Medicine - Columbia, MO
Enterprise Medical Recruiting - Springfield, MO
A Practice Assistant's salary isn't a fixed number. It's shaped by several important factors. Below, we'll explore how your years of experience, geographic location and company size can directly affect your earning potential.
Experience is a primary driver of a Practice Assistant's salary. As you build your skills and take on more complex tasks, your compensation generally increases. Here’s how the average salary grows at different career stages:
| Levels | Salary |
|---|---|
| Benefits ... Level Practice Assistant | $87,641 |
| Benefits ... Level Practice Assistant | $105,195 |
| Practice ... Level Practice Assistant | $98,239 |
| Benefits ... Level Practice Assistant | $118,307 |
| Benefits ... Level Practice Assistant | $157,927 |
What Am I Worth?
Your salary can change significantly depending on where you work. States with a higher cost of living and strong industrial sectors often pay more to attract Practice Assistants. For example, consider the average annual salaries in these key locations:
Salaries can also vary between different cities. Major metropolitan areas or cities with a high demand for technicians often offer more competitive pay. Here are a few examples of average annual salaries in different U.S. cities:
For Practice Assistant roles, the industry you choose can affect earning potential by as much as 40% (the gap between the highest and lowest paying industries). Data shows that the Healthcare and Telecom sectors offer the strongest compensation, at 20% above the average. In contrast, Practice Assistant positions in Transportation or Hospitality & Leisure typically offer lower base pay, as these industries often view Practice Assistant as a support function rather than a direct revenue driver.
| Industry Sector | Average Annual Salary | Average Hourly Rate | Pay vs.Avg |
|---|---|---|---|
| Healthcare | $116,947 | $56.0 | 20% |
| Telecom | $116,947 | $56.0 | 20% |
| Energy & Utilities | $112,074 | $54.0 | 15% |
| Pharmaceuticals | $112,074 | $54.0 | 15% |
| Aerospace & Defense | $107,201 | $52.0 | 10% |
Understanding how a Practice Assistant's annual salary breaks down can help with budgeting. Below, you can see the average hourly rate, weekly pay, and monthly pay for this role. Use the buttons to switch between different pay periods.
| Annual Salary | Monthly Pay | Weekly Pay | Hourly Wage | |
|---|---|---|---|---|
| 75th Percentile | $106,450 | $8,871 | $2,047 | $51 |
| Average | $97,456 | $8,121 | $1,874 | $47 |
| 25th Percentile | $86,176 | $7,181 | $1,657 | $41 |
Ready to take the next step in your career? Browse thousands of current Practice Assistant job openings on our job board. Use the search bar below to find your perfect match.
The Medicus Firm
Columbia, MO
The Medicus Firm | Columbia, MO
Physician Assistant FacultyColumbia, MOPosition Highlights :Enjoy a wonderful quality of life in this Monday through Friday role. Contribute lectures, curr... more
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SSM Health
Saint Louis, MO
SSM Health | Saint Louis, MO
Variety, Flexibility, and Purpose. Find your next Primary Care role at SSM Health. At SSM Health, we are committed to delivering exceptional healthcare ser... more
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Cardiovascular Practice
Saint Louis, MO
Cardiovascular Practice | Saint Louis, MO
Job Description. Job Description. We are a well-established, Physician-Owned Cardiology practice in the West County area of St. Louis, MO. Our office serve... more
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Bloom Healthcare
Saint Louis, MO
Bloom Healthcare | Saint Louis, MO
Practice Ambassador. Bloom Healthcare is a pioneering and employee-owned primary care and hospice practice at the forefront of transforming healthcare deli... more
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Tinkbird
Lees Summit, MO
Tinkbird | Lees Summit, MO
Lee's Summit (Kansas City), MO - Physician Assistant (Part-Time/Flexible Hours). Part-Time Nurse Practitioner / Physician Assistant Opportunity Locations: ... more
7 Days Ago
Broyles 8780, Inc.
Springfield, MO
Broyles 8780, Inc. | Springfield, MO
PERFECT BALANCE OF OUTDOOR BEAUTY AND URBAN AMENITIESRelax and breathe in fresh, crisp air while you and your loved ones take in beautiful sunsets from you... more
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