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As of August 01, 2026, the average salary for a Practice Assistant in South Carolina is $96,112 per year, which breaks down to an hourly rate of $46.
However, a Practice Assistant's salary can vary significantly. Here’s a look at the typical salary range:
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Practice Assistant Salaries by Percentile
| Annual Salary |
Monthly Pay |
Weekly Pay |
Hourly Wage |
|
| 75th Percentile | $104,982 | $8,749 | $2,019 | $50 |
| Average | $96,112 | $8,009 | $1,848 | $46 |
| 25th Percentile | $84,988 | $7,082 | $1,634 | $41 |
Legal Solutions Group - Mount Pleasant, SC
Northeast Healthcare Recruitment - Laurens, SC
Healthcare Recruitment Counselors - Conway, SC
Source Medical, LLC - Vance, SC
A Practice Assistant's salary isn't a fixed number. It's shaped by several important factors. Below, we'll explore how your years of experience, geographic location and company size can directly affect your earning potential.
Experience is a primary driver of a Practice Assistant's salary. As you build your skills and take on more complex tasks, your compensation generally increases. Here’s how the average salary grows at different career stages:
| Levels | Salary |
|---|---|
| Benefits ... Level Practice Assistant | $86,433 |
| Benefits ... Level Practice Assistant | $103,745 |
| Practice ... Level Practice Assistant | $96,885 |
| Benefits ... Level Practice Assistant | $116,675 |
| Benefits ... Level Practice Assistant | $155,750 |
What Am I Worth?
Your salary can change significantly depending on where you work. States with a higher cost of living and strong industrial sectors often pay more to attract Practice Assistants. For example, consider the average annual salaries in these key locations:
Salaries can also vary between different cities. Major metropolitan areas or cities with a high demand for technicians often offer more competitive pay. Here are a few examples of average annual salaries in different U.S. cities:
For Practice Assistant roles, the industry you choose can affect earning potential by as much as 40% (the gap between the highest and lowest paying industries). Data shows that the Healthcare and Telecom sectors offer the strongest compensation, at 20% above the average. In contrast, Practice Assistant positions in Transportation or Hospitality & Leisure typically offer lower base pay, as these industries often view Practice Assistant as a support function rather than a direct revenue driver.
| Industry Sector | Average Annual Salary | Average Hourly Rate | Pay vs.Avg |
|---|---|---|---|
| Healthcare | $115,334 | $55.0 | 20% |
| Telecom | $115,334 | $55.0 | 20% |
| Energy & Utilities | $110,529 | $53.0 | 15% |
| Pharmaceuticals | $110,529 | $53.0 | 15% |
| Aerospace & Defense | $105,723 | $51.0 | 10% |
Understanding how a Practice Assistant's annual salary breaks down can help with budgeting. Below, you can see the average hourly rate, weekly pay, and monthly pay for this role. Use the buttons to switch between different pay periods.
| Annual Salary | Monthly Pay | Weekly Pay | Hourly Wage | |
|---|---|---|---|---|
| 75th Percentile | $104,982 | $8,749 | $2,019 | $50 |
| Average | $96,112 | $8,009 | $1,848 | $46 |
| 25th Percentile | $84,988 | $7,082 | $1,634 | $41 |
Ready to take the next step in your career? Browse thousands of current Practice Assistant job openings on our job board. Use the search bar below to find your perfect match.
Provider Healthcare
Greenville, SC
Provider Healthcare | Greenville, SC
Looking for flexibility now with the option to transition into a long-term role. Join us as a Physician Assistant in South Carolina with Locums-to-Permanen... more
6 Days Ago
Novant Health
Hardeeville, SC
Novant Health | Hardeeville, SC
What We OfferJob Title:Night Nurse Practitioner - Coastal Carolina HospitalLocation: Coastal Carolina Hospital, Hardeeville, SC 1000 Medical Center Dr, Har... more
6 Days Ago
South Carolina
Okatie, SC
South Carolina | Okatie, SC
What We Offer Novant Health is seeking a Primary Care Advanced Practice Provider (APP) to join our growing team in South Carolina. This is an excellent opp... more
7 Days Ago
LifeStance Health
Columbia, SC
LifeStance Health | Columbia, SC
At LifeStance Health, we strive to help individuals, families, and communities with their mental health needs. Everywhere. Every day. It's a lofty goal. we... more
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TELLOS
Greenville, SC
TELLOS | Greenville, SC
Our mission is to allow BCBAs to manage their caseload in away that provides for the best clinical outcomes, a healthy work / life balance for you, and sta... more
6 Days Ago
DirectShifts
Leesville, SC
DirectShifts | Leesville, SC
Medsyndeo is seeking a Primary Care Physician to work in Columbia, SC This is a Full Time Position. My client is very motivated to speak with all intereste... more
6 Days Ago
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