As of July 01, 2026, the average annual salary for acute nurse practitioner in Missouri is $121,581, equivalent to $58 per hour, $2,338 weekly, or $10,132 monthly. These figures, sourced from Salary.com’s real-time job posting scans, highlight competitive earning potential for acute nurse practitioner in cities like San Jose, Santa Clara, and San Francisco.

Annually Salaries for acute nurse practitioner in Missouri vary widely, spanning from $109,066 to $136,243. Most professionals fall between the 25th percentile ($115,030) and 75th percentile ($129,255), while top earners (90th percentile) make $136,243 per year. This $14,225 pay gap underscores opportunities for salary growth through certifications, specialized skills like Collaboration or Psychiatric, or targeting high-paying regions like District of Columbia or California.

Location and experience significantly influence earnings. For example, Missouri acute nurse practitioner often earn 5.0% lower than national averages due to demand from Fortune 17 companies. However, Missouri currently ranks 37 nationwide for acute nurse practitioner job salary. Professionals are advised to focus on high-growth sectors like to offset market challenges.

Based on HR-reported data: a national average with a geographic differential
acute nurse practitioner Salaries by Percentile
Percentile Salary Location Last Updated
10th Percentile acute nurse practitioner Salary $109,066 MO July 01, 2026
25th Percentile acute nurse practitioner Salary $115,030 MO July 01, 2026
50th Percentile acute nurse practitioner Salary $121,581 MO July 01, 2026
75th Percentile acute nurse practitioner Salary $129,255 MO July 01, 2026
90th Percentile acute nurse practitioner Salary $136,243 MO July 01, 2026
25% $115,030 10% $109,066 90% $136,243 75% $129,255 $121,581 50%(Median) Didn’t find job title? Click
Change Search Criteria
Check out acute nurse practitioner jobs in Missouri
Search More acute nurse practitioner Jobs in Missouri

What is An acute nurse practitioner ?

The salary of an acute nurse practitioner (ANP) varies based on factors such as geographic location, years of experience, and the specific healthcare setting. On average, ANPs earn a competitive salary, often ranging from $90,000 to $130,000 annually. Those in metropolitan areas or specialized fields may command higher wages. Additional benefits, including health insurance, retirement plans, and continuing education allowances, often enhance overall compensation. The demand for acute nurse practitioners continues to grow, driven by an increasing need for healthcare services in acute care setti...

Source: (as of 06/04/2025). Read more from

See user submitted job responsibilities for acute nurse practitioner.

Select a city to view specific salary and bonus information for acute nurse practitioner

Loading results...
Location Avg. Salary Date Updated
Location Saint Peters, MO Avg. Salary $138,830 Date Updated July 01, 2026
Location Adrian, MO Avg. Salary $136,959 Date Updated July 01, 2026
Location Advance, MO Avg. Salary $134,202 Date Updated July 01, 2026
Location Agency, MO Avg. Salary $139,167 Date Updated July 01, 2026
Location Alba, MO Avg. Salary $134,144 Date Updated July 01, 2026
Location Albany, MO Avg. Salary $134,608 Date Updated July 01, 2026
Location Aldrich, MO Avg. Salary $130,949 Date Updated July 01, 2026
Location Alexandria, MO Avg. Salary $134,665 Date Updated July 01, 2026
Location Allendale, MO Avg. Salary $134,886 Date Updated July 01, 2026
Location Allenton, MO Avg. Salary $138,639 Date Updated July 01, 2026
Job Openings for acute nurse practitioner in Missouri

Recently searched related titles: Officer In Command, Acute Care Nurse, Acute Care Technician