As of July 01, 2026, the average annual salary for acute nurse practitioner in the US is $127,966, equivalent to $62 per hour, $2,461 weekly, or $10,664 monthly. These figures, sourced from Salary.com’s real-time job posting scans, highlight competitive earning potential for acute nurse practitioner in cities like San Jose, Santa Clara, and San Francisco.

Annually Salaries for acute nurse practitioner in the US vary widely, spanning from $114,794 to $143,398. Most professionals fall between the 25th percentile ($121,072) and 75th percentile ($136,044), while top earners (90th percentile) make $143,398 per year. This $14,972 pay gap underscores opportunities for salary growth through certifications, specialized skills like Collaboration or Psychiatric, or targeting high-paying regions like District of Columbia or California.

Location and experience significantly influence earnings. For example, District of Columbia acute nurse practitioner often earn 10.7% above national averages due to demand from Fortune 17 companies and industry startups. Professionals are advised to focus on high-growth sectors like to offset market challenges.

Based on HR-reported data: a national average with a geographic differential
acute nurse practitioner Salaries by Percentile
Percentile Salary Location Last Updated
10th Percentile acute nurse practitioner Salary $114,794 US July 01, 2026
25th Percentile acute nurse practitioner Salary $121,072 US July 01, 2026
50th Percentile acute nurse practitioner Salary $127,966 US July 01, 2026
75th Percentile acute nurse practitioner Salary $136,044 US July 01, 2026
90th Percentile acute nurse practitioner Salary $143,398 US July 01, 2026
25% $121,072 10% $114,794 90% $143,398 75% $136,044 $127,966 50%(Median) Didn’t find job title? Click
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What is An acute nurse practitioner ?

The salary of an acute nurse practitioner (ANP) varies based on factors such as geographic location, years of experience, and the specific healthcare setting. On average, ANPs earn a competitive salary, often ranging from $90,000 to $130,000 annually. Those in metropolitan areas or specialized fields may command higher wages. Additional benefits, including health insurance, retirement plans, and continuing education allowances, often enhance overall compensation. The demand for acute nurse practitioners continues to grow, driven by an increasing need for healthcare services in acute care setti...

Source: (as of 06/04/2025). Read more from

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Average Base Salary

Core compensation

 
 
 
121072
136044
127966

Average Total Cash Compensation

Includes base and annual incentives

 
 
 
132845
159407
145801
These charts show the average base salary (core compensation), as well as the average total cash compensation for the job of acute nurse practitioner in the United States. The base salary for acute nurse practitioner ranges from $121,072 to $136,044 with the average base salary of $127,966. The total cash compensation, which includes base, and annual incentives, can vary anywhere from $132,845 to $159,407 with the average total cash compensation of $145,801.

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121072
136044

 

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