As of July 01, 2026, the average annual salary for acute nurse practitioner in South Dakota is $116,296, equivalent to $56 per hour, $2,236 weekly, or $9,691 monthly. These figures, sourced from Salary.com’s real-time job posting scans, highlight competitive earning potential for acute nurse practitioner in cities like San Jose, Santa Clara, and San Francisco.

Annually Salaries for acute nurse practitioner in South Dakota vary widely, spanning from $104,325 to $130,320. Most professionals fall between the 25th percentile ($110,030) and 75th percentile ($123,637), while top earners (90th percentile) make $130,320 per year. This $13,607 pay gap underscores opportunities for salary growth through certifications, specialized skills like Collaboration or Psychiatric, or targeting high-paying regions like District of Columbia or California.

Location and experience significantly influence earnings. For example, South Dakota acute nurse practitioner often earn 9.1% lower than national averages due to demand from Fortune 17 companies. However, South Dakota currently ranks 48 nationwide for acute nurse practitioner job salary. Professionals are advised to focus on high-growth sectors like to offset market challenges.

Based on HR-reported data: a national average with a geographic differential
acute nurse practitioner Salaries by Percentile
Percentile Salary Location Last Updated
10th Percentile acute nurse practitioner Salary $104,325 SD July 01, 2026
25th Percentile acute nurse practitioner Salary $110,030 SD July 01, 2026
50th Percentile acute nurse practitioner Salary $116,296 SD July 01, 2026
75th Percentile acute nurse practitioner Salary $123,637 SD July 01, 2026
90th Percentile acute nurse practitioner Salary $130,320 SD July 01, 2026
25% $110,030 10% $104,325 90% $130,320 75% $123,637 $116,296 50%(Median) Didn’t find job title? Click
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General/Non-Invasive Nurse Practitioner

Rush University Medical Center - Aurora, SD

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What is An acute nurse practitioner ?

The salary of an acute nurse practitioner (ANP) varies based on factors such as geographic location, years of experience, and the specific healthcare setting. On average, ANPs earn a competitive salary, often ranging from $90,000 to $130,000 annually. Those in metropolitan areas or specialized fields may command higher wages. Additional benefits, including health insurance, retirement plans, and continuing education allowances, often enhance overall compensation. The demand for acute nurse practitioners continues to grow, driven by an increasing need for healthcare services in acute care setti...

Source: (as of 06/04/2025). Read more from

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Location Avg. Salary Date Updated
Location Deadwood, SD Avg. Salary $131,497 Date Updated July 01, 2026
Location Pierre, SD Avg. Salary $122,722 Date Updated July 01, 2026
Location Watertown, SD Avg. Salary $134,977 Date Updated July 01, 2026
Location Aberdeen, SD Avg. Salary $134,748 Date Updated July 01, 2026
Location Agar, SD Avg. Salary $125,915 Date Updated July 01, 2026
Location Akaska, SD Avg. Salary $133,545 Date Updated July 01, 2026
Location Alcester, SD Avg. Salary $133,759 Date Updated July 01, 2026
Location Alexandria, SD Avg. Salary $134,211 Date Updated July 01, 2026
Location Allen, SD Avg. Salary $133,316 Date Updated July 01, 2026
Location Alpena, SD Avg. Salary $134,438 Date Updated July 01, 2026
Job Openings for acute nurse practitioner in South Dakota

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