As of July 01, 2026, the average annual salary for acute nurse practitioner in Colorado is $130,564, equivalent to $63 per hour, $2,511 weekly, or $10,880 monthly. These figures, sourced from Salary.com’s real-time job posting scans, highlight competitive earning potential for acute nurse practitioner in cities like San Jose, Santa Clara, and San Francisco.

Annually Salaries for acute nurse practitioner in Colorado vary widely, spanning from $117,125 to $146,309. Most professionals fall between the 25th percentile ($123,529) and 75th percentile ($138,806), while top earners (90th percentile) make $146,309 per year. This $15,277 pay gap underscores opportunities for salary growth through certifications, specialized skills like Collaboration or Psychiatric, or targeting high-paying regions like District of Columbia or California.

Location and experience significantly influence earnings. For example, Colorado acute nurse practitioner often earn 2.0% higher than national averages due to demand from Fortune 17 companies. However, Colorado currently ranks 13 nationwide for acute nurse practitioner job salary. Professionals are advised to focus on high-growth sectors like to offset market challenges.

Based on HR-reported data: a national average with a geographic differential
acute nurse practitioner Salaries by Percentile
Percentile Salary Location Last Updated
10th Percentile acute nurse practitioner Salary $117,125 CO July 01, 2026
25th Percentile acute nurse practitioner Salary $123,529 CO July 01, 2026
50th Percentile acute nurse practitioner Salary $130,564 CO July 01, 2026
75th Percentile acute nurse practitioner Salary $138,806 CO July 01, 2026
90th Percentile acute nurse practitioner Salary $146,309 CO July 01, 2026
25% $123,529 10% $117,125 90% $146,309 75% $138,806 $130,564 50%(Median) Didn’t find job title? Click
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Check out acute nurse practitioner jobs in Colorado

Hospitalist Nurse Practitioner

Western Nephrology - Longmont, CO

Nurse Practitioner

Western Nephrology - Lafayette, CO

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Western Nephrology - Longmont, CO

Acute Care Nurse Practitioner

Norton Healthcare - Louisville, CO

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What is An acute nurse practitioner ?

The salary of an acute nurse practitioner (ANP) varies based on factors such as geographic location, years of experience, and the specific healthcare setting. On average, ANPs earn a competitive salary, often ranging from $90,000 to $130,000 annually. Those in metropolitan areas or specialized fields may command higher wages. Additional benefits, including health insurance, retirement plans, and continuing education allowances, often enhance overall compensation. The demand for acute nurse practitioners continues to grow, driven by an increasing need for healthcare services in acute care setti...

Source: (as of 06/04/2025). Read more from

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Location Avg. Salary Date Updated
Location Jefferson, CO Avg. Salary $146,299 Date Updated July 01, 2026
Location Agate, CO Avg. Salary $143,284 Date Updated July 01, 2026
Location Aguilar, CO Avg. Salary $142,557 Date Updated July 01, 2026
Location Akron, CO Avg. Salary $143,064 Date Updated July 01, 2026
Location Alamosa, CO Avg. Salary $144,279 Date Updated July 01, 2026
Location Allenspark, CO Avg. Salary $149,505 Date Updated July 01, 2026
Location Alma, CO Avg. Salary $147,699 Date Updated July 01, 2026
Location Almont, CO Avg. Salary $148,512 Date Updated July 01, 2026
Location Amherst, CO Avg. Salary $142,605 Date Updated July 01, 2026
Location Anton, CO Avg. Salary $142,487 Date Updated July 01, 2026
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