As of July 01, 2026, the average annual salary for acute nurse practitioner in Mississippi is $114,120, equivalent to $55 per hour, $2,195 weekly, or $9,510 monthly. These figures, sourced from Salary.com’s real-time job posting scans, highlight competitive earning potential for acute nurse practitioner in cities like San Jose, Santa Clara, and San Francisco.

Annually Salaries for acute nurse practitioner in Mississippi vary widely, spanning from $102,374 to $127,883. Most professionals fall between the 25th percentile ($107,972) and 75th percentile ($121,324), while top earners (90th percentile) make $127,883 per year. This $13,352 pay gap underscores opportunities for salary growth through certifications, specialized skills like Collaboration or Psychiatric, or targeting high-paying regions like District of Columbia or California.

Location and experience significantly influence earnings. For example, Mississippi acute nurse practitioner often earn 10.8% lower than national averages due to demand from Fortune 17 companies. However, Mississippi currently ranks 51 nationwide for acute nurse practitioner job salary. Professionals are advised to focus on high-growth sectors like to offset market challenges.

Based on HR-reported data: a national average with a geographic differential
acute nurse practitioner Salaries by Percentile
Percentile Salary Location Last Updated
10th Percentile acute nurse practitioner Salary $102,374 MS July 01, 2026
25th Percentile acute nurse practitioner Salary $107,972 MS July 01, 2026
50th Percentile acute nurse practitioner Salary $114,120 MS July 01, 2026
75th Percentile acute nurse practitioner Salary $121,324 MS July 01, 2026
90th Percentile acute nurse practitioner Salary $127,883 MS July 01, 2026
25% $107,972 10% $102,374 90% $127,883 75% $121,324 $114,120 50%(Median) Didn’t find job title? Click
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PSYCHIATRIC NURSE PRACTITIONER

U.S. Army 2nd Medical Recruiting Battalion - Raleigh, MS

NP, Nurse Practitioner - Pulmonary

Christus Health - Longview, MS

Medical Aesthetics & Vein Care Nurse Practitioner

Vein Institute of South MS - Lamar Park, MS

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What is An acute nurse practitioner ?

The salary of an acute nurse practitioner (ANP) varies based on factors such as geographic location, years of experience, and the specific healthcare setting. On average, ANPs earn a competitive salary, often ranging from $90,000 to $130,000 annually. Those in metropolitan areas or specialized fields may command higher wages. Additional benefits, including health insurance, retirement plans, and continuing education allowances, often enhance overall compensation. The demand for acute nurse practitioners continues to grow, driven by an increasing need for healthcare services in acute care setti...

Source: (as of 06/04/2025). Read more from

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Location Avg. Salary Date Updated
Location Olive Branch, MS Avg. Salary $134,920 Date Updated July 01, 2026
Location Abbeville, MS Avg. Salary $128,403 Date Updated July 01, 2026
Location Aberdeen, MS Avg. Salary $125,040 Date Updated July 01, 2026
Location Ackerman, MS Avg. Salary $126,149 Date Updated July 01, 2026
Location Algoma, MS Avg. Salary $127,456 Date Updated July 01, 2026
Location Alligator, MS Avg. Salary $125,768 Date Updated July 01, 2026
Location Amory, MS Avg. Salary $125,651 Date Updated July 01, 2026
Location Anguilla, MS Avg. Salary $128,147 Date Updated July 01, 2026
Location Arcola, MS Avg. Salary $129,495 Date Updated July 01, 2026
Location Arkabutla, MS Avg. Salary $132,792 Date Updated July 01, 2026
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