As of July 01, 2026, the average annual salary for acute nurse practitioner in North Carolina is $121,607, equivalent to $58 per hour, $2,339 weekly, or $10,134 monthly. These figures, sourced from Salary.com’s real-time job posting scans, highlight competitive earning potential for acute nurse practitioner in cities like San Jose, Santa Clara, and San Francisco.

Annually Salaries for acute nurse practitioner in North Carolina vary widely, spanning from $109,089 to $136,271. Most professionals fall between the 25th percentile ($115,054) and 75th percentile ($129,283), while top earners (90th percentile) make $136,271 per year. This $14,229 pay gap underscores opportunities for salary growth through certifications, specialized skills like Collaboration or Psychiatric, or targeting high-paying regions like District of Columbia or California.

Location and experience significantly influence earnings. For example, North Carolina acute nurse practitioner often earn 5.0% lower than national averages due to demand from Fortune 17 companies. However, North Carolina currently ranks 36 nationwide for acute nurse practitioner job salary. Professionals are advised to focus on high-growth sectors like to offset market challenges.

Based on HR-reported data: a national average with a geographic differential
acute nurse practitioner Salaries by Percentile
Percentile Salary Location Last Updated
10th Percentile acute nurse practitioner Salary $109,089 NC July 01, 2026
25th Percentile acute nurse practitioner Salary $115,054 NC July 01, 2026
50th Percentile acute nurse practitioner Salary $121,607 NC July 01, 2026
75th Percentile acute nurse practitioner Salary $129,283 NC July 01, 2026
90th Percentile acute nurse practitioner Salary $136,271 NC July 01, 2026
25% $115,054 10% $109,089 90% $136,271 75% $129,283 $121,607 50%(Median) Didn’t find job title? Click
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Pediatrix Medical Group - Victory, NC

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What is An acute nurse practitioner ?

The salary of an acute nurse practitioner (ANP) varies based on factors such as geographic location, years of experience, and the specific healthcare setting. On average, ANPs earn a competitive salary, often ranging from $90,000 to $130,000 annually. Those in metropolitan areas or specialized fields may command higher wages. Additional benefits, including health insurance, retirement plans, and continuing education allowances, often enhance overall compensation. The demand for acute nurse practitioners continues to grow, driven by an increasing need for healthcare services in acute care setti...

Source: (as of 06/04/2025). Read more from

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Location Avg. Salary Date Updated
Location Aberdeen, NC Avg. Salary $132,069 Date Updated July 01, 2026
Location Advance, NC Avg. Salary $134,830 Date Updated July 01, 2026
Location Ahoskie, NC Avg. Salary $132,234 Date Updated July 01, 2026
Location Alamance, NC Avg. Salary $135,191 Date Updated July 01, 2026
Location Albemarle, NC Avg. Salary $134,942 Date Updated July 01, 2026
Location Albertson, NC Avg. Salary $131,248 Date Updated July 01, 2026
Location Alexander, NC Avg. Salary $133,988 Date Updated July 01, 2026
Location Alexis, NC Avg. Salary $139,200 Date Updated July 01, 2026
Location Alliance, NC Avg. Salary $130,859 Date Updated July 01, 2026
Location Almond, NC Avg. Salary $131,782 Date Updated July 01, 2026
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