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Regulatory Affairs Manager Salary in Irvine, CA

How much does a Regulatory Affairs Manager make in Irvine, CA?

As of March 01, 2026, the average salary for a Regulatory Affairs Manager in Irvine, CA is $165,993 per year, which breaks down to an hourly rate of $80.

However, a Regulatory Affairs Manager's salary can vary significantly. Here’s a look at the typical salary range:

  • Top Earners (90th percentile): $193,208
  • Majority Range (25th-75th percentile): $149,112 to $180,238
  • Entry-Level (10th percentile): $133,743
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View as table View as graph 25% $149,112 10% $133,743 90% $193,208 75% $180,238 $165,993 50%(Median) Didn’t find job title? Click

Regulatory Affairs Manager Salaries by Percentile

Annual
Salary
Monthly
Pay
Weekly
Pay
Hourly
Wage
75th Percentile $180,238 $15,020 $3,466 $87
Average $165,993 $13,833 $3,192 $80
25th Percentile $149,112 $12,426 $2,868 $72
Check out Regulatory Affairs Manager Job Openings in Irvine, CA
Regulatory Affairs Manager

Intuitive - Sunnyvale, CA

Regulatory Affairs Program Manager

UC Irvine - King, CA

Regulatory Affairs Project Manager

Abbott - Sylmar, CA

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Key Factors That Influence Regulatory Affairs Manager Salaries

A Regulatory Affairs Manager's salary isn't a fixed number. It's shaped by several important factors. Below, we'll explore how your years of experience, geographic location, skills and company size can directly affect your earning potential.

How Experience Level Affects Regulatory Affairs Manager Salaries?

Experience is a primary driver of a Regulatory Affairs Manager's salary. As you build your skills and take on more complex tasks, your compensation generally increases. Here's how the average salary grows at different career stages:

  • Regulatory Affairs Specialist III (4-7 years): $114,184
  • Regulatory Affairs Specialist IV (7+ years): $144,238
  • Regulatory Affairs Manager (7+ years): $165,993
  • Regulatory Affairs Senior Manager (7+ years): $195,846
  • Regulatory Affairs Director (7+ years): $221,586
Job Role Years of Experience Average Salary
Regulatory Affairs Specialist III4-7 years$114,184
Regulatory Affairs Specialist IV7+ years$144,238
Regulatory Affairs Manager7+ years$165,993
Regulatory Affairs Senior Manager7+ years$195,846
Regulatory Affairs Director7+ years$221,586
$114,184 Regulator...
$144,238 Regulator...
$165,993 Regulator...
$195,846 Regulator...
$221,586 Regulator...
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What Am I Worth?

Top Paying Cities for Regulatory Affairs Managers

Salaries can also vary between different cities. Major metropolitan areas or cities with a high demand for technicians often offer more competitive pay. Here are a few examples of average annual salaries in different U.S. cities:

  • San Jose: $190,507
  • San Francisco: $188,634
  • Oakland: $184,450

What Skills Can Increase a Regulatory Affairs Manager's Salary?

Demanded Skills for the Role:

  • Leadership (Mentioned in 8.83% Job Postings): Knowledge of and ability to employ effective strategies that motivate and guide other members within our business to achieve optimum results.
  • Clinical Trial (Mentioned in 1.44% Job Postings): Clinical trials are prospective biomedical or behavioral research studies on human participants designed to answer specific questions about biomedical or behavioral interventions, including new treatments.
  • Procurement (Mentioned in 1.2% Job Postings): Procurement is the process of finding and agreeing to terms, and acquiring goods, services, or works from an external source, often via a tendering or competitive bidding process. Procurement is used to ensure the buyer receives goods, services, or works at the best possible price when aspects such as quality, quantity, time, and location are compared. Corporations and public bodies often define processes intended to promote fair and open competition for their business while minimizing risks such as exposure to fraud and collusion. Almost all purchasing decisions include factors such as delivery and handling, marginal benefit, and price fluctuations. Procurement generally involves making buying decisions under conditions of scarcity. If sound data is available, it is good practice to make use of economic analysis methods such as cost-benefit analysis or cost-utility analysis.
See More Skills
Skills Demand Percentage
Leadership 8.83%
Clinical Trial 1.44%
Procurement 1.2%
What skills can make your compensation higher?
Mastering certain specialized skills can lead to a significant increase in pay. Here are examples of skills and the potential impact they can have on a Regulatory Affairs Manager's salary.
  • Biotechnology: Can increase your salary by up to 3%.
  • Alignment: Can increase your salary by up to 3%.
  • Coaching: Can increase your salary by up to 3%.
Skill Salary Salary % Increase
Biotechnology
$170,973
3%
Alignment
$170,973
3%
Coaching
$170,973
3%
Project Management
$169,313
2%
SOP
$169,313
2%
Commitment
$169,313
2%
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Regulatory Affairs Manager Salary: Hourly Rate, Weekly Pay, and Monthly Pay

Understanding how a Regulatory Affairs Manager's annual salary breaks down can help with budgeting. Below, you can see the average hourly rate, weekly pay, and monthly pay for this role. Use the buttons to switch between different pay periods.

Last Updated on March 01, 2026

Regulatory Affairs Manager Salary Growth & Career Path

Promotions are the fastest way to increase your earnings. As a Regulatory Affairs Manager, you have the following paths for advancement. The table below compares the salary raises for common next-step roles. By comparing these figures, you can choose the career path that best meets your financial goals.

Regulatory Affairs Manager Salary Growth and Career Path
Next Step Role Estimate Salary Projected Raise
Regulatory Documentation Senior Manager $185,441 12%
Regulatory Affairs Senior Manager $195,846 18%
Product Regulatory Senior Manager $185,441 12%

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Cost of Living In Irvine, CA

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