How much does a Medical Affairs Director make?

As of March 01, 2025, the average annual salary for a Medical Affairs Director in the United States is $248,151. According to Salary.com, salaries can range from a low of $204,891 to a high of $298,035, with most professionals earning between $225,507 and $274,262.

Based on HR-reported data: a national average with a geographic differential
Medical Affairs Director Salaries by Percentile
Percentile Salary Location Last Updated
10th Percentile Medical Affairs Director Salary $204,891 US March 01, 2025
25th Percentile Medical Affairs Director Salary $225,507 US March 01, 2025
50th Percentile Medical Affairs Director Salary $248,151 US March 01, 2025
75th Percentile Medical Affairs Director Salary $274,262 US March 01, 2025
90th Percentile Medical Affairs Director Salary $298,035 US March 01, 2025
25% $225,507 10% $204,891 90% $298,035 75% $274,262 $248,151 50%(Median) Didn’t find job title? Click
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Medical Affairs Director

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  1. This Job:

    Medical Affairs Director


    JD, MD, PhD or Equivalent

  2. Up a level:

    Medical Director


    JD, MD, PhD or Equivalent

Understand the total compensation opportunity for a Medical Affairs Director, base salary plus other pay elements

Average Base Salary

Core compensation

 
 
 
225507
274262
248151

Average Total Cash Compensation

Includes base and annual incentives

 
 
 
225507
274262
248151
These charts show the average base salary (core compensation), as well as the average total cash compensation for the job of Medical Affairs Director in the United States. The base salary for Medical Affairs Director ranges from $225,507 to $274,262 with the average base salary of $248,151. The total cash compensation, which includes base, and annual incentives, can vary anywhere from $225,507 to $274,262 with the average total cash compensation of $248,151.

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225507
274262

 

Jobs with a similar salary range to Medical Affairs Director : Medical Superintendent