What is the salary range of a Manager, Clinical Operations?
As of August 01, 2025, the average annual salary for a Manager, Clinical Operations in Durham, CA ranges from $162,972 (25th percentile) to $217,161 (75th percentile), with a median annual salary of $183,997 and an hourly rate of $88. A Manager, Clinical Operations's salary is shaped by several key factors, including experience level, specific skills, industry differences, company size, and more. Below, we'll explore how each of these influences compensation.