What is the salary range of a Registered Nurse?
As of August 01, 2025, the average annual salary for a Registered Nurse in North Fort Myers, FL ranges from $81,859 (25th percentile) to $100,789 (75th percentile), with a median annual salary of $89,640 and an hourly rate of $43. A Registered Nurse's salary is shaped by several key factors, including experience level, specific skills, industry differences, company size, and more. Below, we'll explore how each of these influences compensation.